Abstract | Cilj: Istražiti učestalost i utjecaj pretilosti žena prije trudnoće i povezanost visokog BMI-a
majke prije trudnoće s ocjenom fetalnoga rasta i razvoja.
Ustroj istraživanja: Retrospektivno presječno istraživanje.
Mjesto istraživanja: KBC Split, Klinika za ženske bolesti i porode.
Sudionici: Analizirani su podatci 4678 trudnica i njihove novorođenčadi tijekom 2008.-2009.
godine.
Glavne mjere ishoda: Podatci su dobiveni uvidom u medicinsku dokumentaciju.
Kategorizacija indeksa tjelesne mase (BMI-a) prije trudnoće provedena je prema standardima
Svjetske Zdravstvene Organizacije, a ocjena fetalnoga rasta prema standardima Klinike.
Rezultati: Ispitivanu skupinu pretilih žena prije trudnoće sačinjavalo je 89 (1,9%), a
kontrolnu 3688 (78,8%) svih trudnica Klinike u narečenom razdoblju. Pretile trudnice češće
su bile višerotke i rađale u starijoj dobnoj skupini. Pretile trudnice bile su starije (28,7±3,7 vs.
27,2±3,9; P<0.001), manjeg prirasta mase (11,7±4,9 vs. 15,6±4,5), češće su rađale carskim
rezom (22,4% vs. 15,3%; P=0,012) uz više makrosomne (2,2% vs. 7,8%; P<0,001) i
hipertrofične novorođenčadi (19,2% vs. 9,2%; P=0,022). Veća je pojavnost prijevremenog
porođaja u skupini pretilih trudnica u odnosu prema onima urednog BMI-a (t=1,74;
P =0,081).
Zaključak: Debljina žene prije trudnoće je povezana s ocjenom fetalnoga rasta. Perinatalni
ishod trudnoće žena pretilih prije trudnoće nepovoljniji je nego u onih uredne tjelesne građe. |
Abstract (english) | Objectives: Prevalence to be shown of high maternal pre-pregnancy BMI and association
with fetal growth and development.
Design: Retrospective cross-sectional study.
Settings: Hospital Clinical Center Split, The Department of the Gynecology and Obstetrics.
Participans: The data have been collected from 4678 pregnat women and their newborns.
Main outcomes measures: Medical documentation has been used on informations gathering.
Maternal prepregnancy BMIs were categorized on the basis of the WHO standards and fetal
growth index was based on the Department standards.
Results: The pre-pregnancy BMI classified 89 (1,9%) women as upweight and 3688 (78,8%)
as a normal weight. Upweight women were more likely multiparaous and high gynecologic
age. Obese woman were older (P<0,001), had less weight gain (P<0,001) and prenatal
admissions (P=0,003), more of them were multiparae (P<0,001) and often needed cesarean
section (P=0,012), they were more likely to develop pre-eclampsia (P=0,009) and to deliver
macrosomic (P<0,001) or/and hypertrophic (P=0,022) infants. Preterm birth rate was higher
among pre-pregnancy obese woman (t=1,74; P=0,081).
Conclusion: High pre-pregnancy BMI is associated with fetal growth. Pre-pregnancy obese
women are at the great perinatal risk compared to women with normal BMI. |