Abstract | Cilj: Cilj rada je bio procijeniti pojavnost i specifične epidemiološke značajke raka vrata maternice stanovnica Zadarske županije od 2007. do 2016. godine te moguće razlike u odnosu na druge županije Hrvatske.
Materijal i metode: Izvor podataka za bolesnice su bili agregirani podatci Zdravstveno-statističkih ljetopisa Zadarske i Istarske županije, Hrvatskog zavoda za javno zdravstvo i Registra za rak. Državni zavod za statistiku je bio izvor podataka o stanovništvu. Standardizirane stope su izračunate na Europsko standardno stanovništvo 2013. godine (ESP 2013).
Rezultati: U Zadarskoj županiji (ZŽ) u razdoblju od 2007. do 2016. god. od raka vrata maternice (RVM) ukupno je bilo 537 bolesnica. Prosječna godišnja stopa pobola, koja predstavlja približnu vrijednost stope prevalencije RVM za ZŽ istog razdoblja je 62,17/100 000. Novooboljelih od RVM u ZŽ u razdoblju od 2007. do 2014. godine je bilo ukupno 99. Prosječno godišnje je 12 novooboljelih. Prosječna godišnja dobno standardizirana stopa novooboljelih je 14,48/100 000. Počevši od dobne skupine 25-29 godina u svim petogodišnjim dobnim razredima do dobi 85 i više godina života registrirane su novooboljele od RVM. Dobno najmlađe novooboljele bile su u dobnom razredu od 25 do 29 godina. Najstarija novooboljela je bila dobi 85 i više godina. Najveći broj i najveće dobno-specifične stope incidencije su bili u kasnijoj fertilnoj dobi 40-49 godina, s 33 novooboljele, što čini 1/3 svih novooboljelih. Ukupno je od RVM 31 umrla u ZŽ u razdoblju od 2007.do 2016.godine. Prosječno godišnje su 3 umrle. Prosječna godišnja gruba stopa smrtnosti od RVM za ZŽ je iznosila 3,60/100 000. Najveći broj umrlih u jednoj godini je bio 5 umrlih (2009. i 2015.). Ni jedan smrtni ishod nije bio u 2016. godini. Ni jedne smrti od RVM nije bilo do 34 godine života. Najmlađa dob umrlih žena od RVM bila je u srednjoj fertilnoj dobi u dobnom razredu 35-39 godina, 2 umrle. Prema dobi najveći broj smrti je 5 umrlih u dobnom razredu 40-44 godine. Ukupno u fertilnoj dobi 15-49 godina je bilo 10 umrlih, a u poslijefertilnoj 50-64 godine 11 umrlih. U dobi ≥65 godina bilo je 10 umrlih. Od ukupno 31 umrle, 2/3 umrlih (21) pripadaju kategoriji prijevremenih smrti dobi prije 65 godina života. Najveća gruba dobno-specifična stopa smrtnosti je bila u dobnom razredu 80-84 godine (11,15/100 000). Slijedi dobni razred 40-45 godina (9,25/100 000). Najmanja gruba dobno-specifična stopa smrtnosti je bila za dobni razred 35-39 godina (3,65/100 000).
Zaključak: Rezultati ovog rada su pokazali da u ZŽ u razdoblju od 2007. do 2016. godine najveći broj i najveće dobno-specifične stope incidencije RVM su bili u kasnijoj fertilnoj dobi 40-49 godina. U istom razdoblju ukupno je umrla 31 stanovnica ZŽ od RVM, koje po standardima suvremene zdravstvene zaštite razvijenih zemalja nisu smjele umrijeti. |
Abstract (english) | Aim: The aim of the work was to evaluate the appearance and specific epidemiological features of cervix cancer of the Zadar County population from 2007 to 2016 and the possible differences with reference to other counties in Croatia.
Material and methods: The patient source of data were aggregated data from the Health-Statistics Chronicles of Zadar and Istria counties, Croatian Health Care Institute and Cancer Register. The Statistics State Institute was the source of data on the population. Standardized rates were calculated according to the 2013 European Standard for Population (ESP 2013).
Results: In the period from 2007 to 2016 Zadar County had a total of 537 cervix cancer patients. The median annual morbidity rate, which represented an approximate value of cervix cancer prevalence rate for Zadar County during the same period, was 62.17/100,000. New cases of cervix cancer in ZC from 2007 to 2014 amounted to a total of 99. The annual average is 12 new cases. The average annual age standardizes rate of new cases is 14.48/100,000. Starting from the age group 25-29 years in all the five-year-period up to the group of 85 years of age and more, new cases of cervix cancer have been registered. The youngest age of new cases was from 25 to 29 years, and the oldest was of 85 years and more. The highest number and the highest age-specific incidence rate were in the later fertile age from 40 to 49 years with 33 new cases which made up 1/3 of all new cases. A total of 31 patients died of cervix cancer in ZC in the 2007-2016 period. An average of 3 patients died each year. The rough average mortality rate of cervix cancer in ZC was 3.60/100,000. The highest number of deaths in one year was 5 deaths (years 2009 and 2015). There was no mortality result in year 2016. None of the cervix cancer deaths were under the age of 34. The youngest cervix cancer death was in the average fertile age, the age group of 35-39 years, with 2 deaths. The highest number of deaths according to age was 5 deaths in the age group of 40-44 years. In the fertile period of 15-49 years of age, there were 10 deaths, while in the post-fertile period of 50-64 years of age there were 11 deaths. In the age ≥65 there were 10 deaths. 2/3 (21) of the 31 deceased belong to the category of early death age prior to 65 years of age. The highest rough age-specific mortality rate was in the age group of 80-84 years (11.15/100,000). The 40-45 years of age group followed (9.25/100,000). The lowest rough age-specific mortality rate was in the age group of 35-39 years (3.65/100,000).
Conclusion: The results of this study have shown that in ZC, during the period from 2007 to 2016, the highest number and highest age-specific rate incidence of cervix cancer was in the late fertile age of 40-49 years. In that same period, a total of 31 ZC inhabitants died of cervix cancer, which, according to contemporary health protection standards in developed countries, should not have died. |