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master's thesis
Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode
Split: University of Split, School of Medicine, 2018. urn:nbn:hr:171:166006
Škorput, Gabriela
University of Split
School of Medicine

Institutional repository: MEFST Repository

Cite this document

Škorput, G. (2018). Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:166006

Škorput, Gabriela. "Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode." Master's thesis, University of Split, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:171:166006

Škorput, Gabriela. "Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode." Master's thesis, University of Split, School of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:171:166006

Škorput, G. (2018). 'Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode', Master's thesis, University of Split, School of Medicine, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:171:166006

Škorput G. Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode [Master's thesis]. Split: University of Split, School of Medicine; 2018 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:171:166006

G. Škorput, "Kvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode", Master's thesis, University of Split, School of Medicine, Split, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:171:166006

Metadata
TitleKvalitativna analiza dječjih šampona i kupki primjenom GC-MS metode
Title (english)Qualitative analysis of baby shampoo and baths by GC-MS method
AuthorGabriela Škorput
MentorDavorka Sutlović (mentor)
MentorMaja Veršić Bratinčević (sumentor)
Committee memberNeira Puizina Ivić (predsjednik povjerenstva)
Committee memberIvana Mudnić (član povjerenstva)
Committee memberDavorka Sutlović (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2018, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Ciljevi istraživanja: Kvalitativna analiza dječjih krema, usporedba dobivenih rezultata s deklaracijom proizvoda te pronalazak poveznice između cijene proizvoda i prisusCiljevi istraživanja: Kvalitativnom analizom ispitati sastav dječjih šampona i kupki, usporediti navode deklaracije s dobivenim rezultatima, ispitati prisustvo štetnih sastojaka te prikazati korelaciju dobivenih rezultata s mjestom prodaje proizvoda. Materijali i metode: Ispitano je 10 uzoraka dječjih šampona i kupki. Za analitičku pripremu uzoraka korištene su staklene Petrijeve zdjelice na koje je nanesen uzorak mase 0,1 g. Uzorci su ekstrahirani smjesom organskih otapala: kloroforma, etil acetata i N-heksana u jednakom omjeru. Kvalitativna analiza je izvršena GC-MS metodom. Za usporedbu otapala uzorak 1 otopljen je i u čistom kloroformu. Rezultati: Kvalitativnom analizom u uzorcima je detektirano u rasponu 19-54 supstanci, dok ih je na pojedinačnim deklaracijama navedeno u rasponu 12-25. Posebno je ispitivano prisustvo štetnih sastojaka: parabena, dietilftalata, fenoksietanola te metilizotiazolinona. Metilizotiazolinon nije detektiran u nijednom uzorku, iako je deklariran u uzorku 6. Od ukupno 10 ispitivanih uzoraka, u 4 uzorka je dokazano prisustvo nepoželjnih sastojaka. U samo jednom uzorku detektiran je paraben. Prisutnost ftalata detektirana je u svim uzorcima, međutim jedino kod uzorka 9 smatra se da nije rezultat onečišćenja. Usporedbom kromatograma uzorka 1, dokazano je da smjesa organskih otapala daje jasnije signale u odnosu na sami kloroform. Zaključak: Ovim istraživanjem pokazano je odstupanje deklaracija u prosjeku od 12 supstanci. Podudarnost deklaracija s brojem detektiranih tvari pokazala se najlošijom kod proizvoda dostupnih isključivo u ljekarnama i specijaliziranim prodavaonicama, no upravo u navedenim proizvodima detektirano je najmanje štetnih sastojaka. Od 4 uzorka iz linije za poseban tip kože, za 3 je pokazano da odgovaraju svojoj namijeni.
Abstract (english)
Objectives: Qualitative determination of ingredients in baby shampoos and baths, as well as the comparison of the results with declarations. Examine the presence of harmful ingredients and to find a correlation between the place of product sales and obtained results. Materials and methods: Ten samples of baby shampoos and baths were examined. Samples were extracted with a mixture of organic solvents, chloroform, ethyl acetate and N-hexane in equal proportions. Qualitative analysis was performed by a GC-MS method. For comparison of the results, sample 1 was dissolved in pure chloroform. Results: By qualitative analysis of the samples 19-54 substances were detected, while 12-25 substances were listed on each declarations. The presence of harmful substances such as parabens, diethyl phthalates, phenoxyethanol and methylisothiazolinone was investigated. Methylisothiazolinone was not detected in any of the samples, although it was declared in sample No. 6. Out of a total of 10 tested samples, 4 samples showed the presence of undesirable ingredients. Paraben was detected in only one sample. The presence of phthalate was detected in all samples, but only in sample 9 it is considered not to be the result of contamination. By comparing chromatograms of sample 1, it was shown that the mixture of organic solvents gave clearer signals relative to the chloroform itself. Conclusion: This study showed a deviation of the declaration on an average of 12 substances. The conformity of the declaration compared with the number of detected substances was the worst in products available only in pharmacies and specialized stores, but the least harmful ingredients were detected in these products. Of the 4 samples from the line for a special type of skin, for 3 is shown to suit their purpose.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:166006
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-01-30 12:26:27