| Abstract | Objectives: Living on hemodialysis is a challenge to many patients, impacting various aspects of their lives and ultimately influencing their quality of life. The aim of this was to determine the differences in quality of life between male and female patients on hemodialysis and to evaluate the relationship between quality of life and malnutrition-inflammation score.
Patients and methods: This study included 50 patients in total, 26 males and 24 females. To evaluate health related quality of life the Short Form-36 questionnaire was utilized. This is a multifunctional, non-disease specific 36 question health survey in 8 different domains. In addition to this, the malnutrition-inflammation score (MIS) which included four sections (nutritional history, physical examination, body mass index, and laboratory values) was determined.
Results: Females had statistically significantly lower scores than males in the following domains: physical functioning (48.7±35.0 vs. 68.4±26.9; P=0.029), energy/vitality (70.4±20.1 vs. 84.6±12.0; P=0.004), emotional well-being (71.8±18.1 vs. 83.5±10.1; P=0.008), pain (75.5±36.8 vs. 95.7±14.2; P=0.005) and general health perception (37.1±10.4 vs. 44.6±14.9; P=0.042). Older age was associated with lower quality of life in 4 of the questionnaire domains: physical functioning (r= -0.334; P=0.017), role limitations both physical (r= -0.298; P=0.035) and emotional (r= -0.361; P=0.010) and social functioning (r= -0.309; P=0.029). Moreover, the duration of the chronic kidney disease only negatively influenced the domain of general health perception (r= -0.283; P=0.047). The amount of time on dialysis negatively affected the domains of energy/vitality (r= -0.326; P=0.020) and emotional well-being (r= -0.282; P=0.047). Additionally, there was statistically significant negative correlation between MIS and all domains of SF-36 questionnaire.
Conclusion: We can conclude that female patients on dialysis had lower health related quality of life when compared to men. Furthermore, quality of life inversely correlated with malnutrition-inflammation status. |
| Abstract (croatian) | Ciljevi: Život na hemodijalizi izazov je za mnoge pacijente, koji utječe na različite aspekte njihovog života i naposljetku utječe na njihovu kvalitetu života. Cilj ovog istraživanja bio je utvrditi razlike u kvaliteti života između muškaraca i žena koje su na hemodijalizi i utvrditi vezu između kvalitete života i zbira pothranjenosti.
Pacijenti i metode: Ispitivanje je obuhvatilo ukupno 50 pacijenata, 26 muškaraca i 24 žene. Za procjenu zdravstvene kvalitete života korišten je Upitnih zdravstvenog stanja SF-36. Ovo je multifunkcionalni, bolest nespecifični, zdravstveni upitnik s 36 pitanja u 8 različitih domena. Uz to, izračunat je i malnutricijsko-inflamacijski zbir (MIS) koji je uključivao četiri dijela (povijest prehrane, fizički pregled, indeks tjelesne mase i laboratorijske vrijednosti).
Rezultati: Žene su imale statistički značajno niži zbir od muškaraca u sljedećim domenama: fizičko funkcioniranje (48,7±35,0 nasuprot 68,4±26,9; P=0,029), energija/vitalnost (70,4±20,1 nasuprot 84,6±12,0; P=0,004), emocionalno blagostanje (71,8±18,1 nasuprot 83,5±10,1; P=0,008), bol (75,5±36,8 nasuprot 95,7±14,2; P=0,005) i percepcija općeg zdravlja (37,1±10,4 nasuprot 44,6±14,9; P=0,042). Starija dob bila je povezana s nižom kvalitetom života u 4 područja upitnika: fizičko funkcioniranje (r=-0,334; P=0,017), ograničenja zbog fizičkih (r=-0,361; P=0,010) i emocionalnih poteškoća (r=-0,361; P=0,010) i socijalno funkcioniranje (r=-0,309; P= 0,029). Nadalje, trajanje kronične bubrežne bolesti samo je negativno utjecalo na domenu percepcije općeg zdravlja (r=-0.283; P=0.047). Vrijeme provedeno na dijalizi negativno je utjecalo na domenu energija/vitalnost (r= -0,326; P=0,020) i emocionalno blagostanje (r=-0,282; P=0,047). Pronađena je statistički značajna negativna korelacija između MIS zbira i svih domena SF-36 upitnika.
Zaključak: Žene su imale nižu procjenu kvalitete života u usporedbi s muškarcima. Nadalje, kvaliteta života je negativno korelirala sa zbirom pothranjenosti. |
