prikaz prve stranice dokumenta Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period
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Scientific paper - Original scientific paper
Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period
Diagnostics, 14 (2024), 23; 1-15. https://doi.org/10.3390/diagnostics14232645
Sekelj Fures, Jadranka; Duranovic, Vlasta; Lenicek Krleza, Jasna; Katusic Bojanac, Ana; Loncar, Lana; Dakovic, Ivana; Pejic-Rosko, Sanja; Vulin, Katarina; Pilon-Far, Andrijana; Simic Klaric, Andrea

Institutional repository: Repository of General County Hospital Požega

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Sekelj Fures, J., Duranovic, V., Lenicek Krleza, J., Katusic Bojanac, A., Loncar, L., Dakovic, I. ... Simic Klaric, A. (2024). Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period. Diagnostics, 14. (23), 1-15. doi: 10.3390/diagnostics14232645

Sekelj Fures, Jadranka, et al. "Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period." Diagnostics, vol. 14, no. 23, 2024, pp. 1-15. https://doi.org/10.3390/diagnostics14232645

Sekelj Fures, Jadranka, Vlasta Duranovic, Jasna Lenicek Krleza, Ana Katusic Bojanac, Lana Loncar, Ivana Dakovic, Sanja Pejic Rosko, Katarina Vulin, Andrijana Pilon Far and Andrea Simic Klaric. "Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period." Diagnostics 14, no. 23 (2024): 1-15. https://doi.org/10.3390/diagnostics14232645

Sekelj Fures, J., et al. (2024) 'Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period', Diagnostics, 14(23), pp. 1-15. doi: 10.3390/diagnostics14232645

Sekelj Fures J, Duranovic V, Lenicek Krleza J, Katusic Bojanac A, Loncar L, Dakovic I, and sur.. Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period. Diagnostics [Internet]. 2024 November 24 [cited 2024 December 28];14(23):1-15. doi: 10.3390/diagnostics14232645

J. Sekelj Fures, et al., "Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period", Diagnostics, vol. 14, no. 23, pp. 1-15, November 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:267:236049. [Accessed: 28 December 2024]

Metadata
Title (english)Calcitonin-Gene-Related Peptide in Migraine and Tension-Type Headache in Children During Interictal Period
AuthorJadranka Sekelj Fures
AuthorVlasta Duranovic
AuthorJasna Lenicek Krleza
AuthorAna Katusic Bojanac
AuthorLana Loncar
AuthorIvana Dakovic
AuthorSanja Pejic-Rosko
AuthorKatarina Vulin
AuthorAndrijana Pilon-Far
AuthorAndrea Simic Klaric
Author's institution(County General Hospital Požega)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Background/Objectives: Research on calcitonin-gene-related peptide (CGRP) in adult migraine is extensive, but its role in childhood migraine remains unclear. This study aimed to evaluate serum CGRP levels in children experiencing migraine and tension-type headache (TTH) during interictal periods, comparing these levels to age-matched healthy controls. Methods: A total of 66 migraine patients, 59 with TTH, and 53 controls were recruited and stratified by headache onset age: under 7, 7–12, and over 12 years. CGRP levels were quantified using enzyme-linked immunosorbent assay (ELISA). Results: The migraine patients showed significantly higher serum CGRP levels than both the TTH patients and the controls (p < 0.001), with no significant difference between the latter two groups. Among the migraine patients, those without aura (MO) exhibited higher CGRP levels than those with aura (MA). The CGRP levels were lower in the. MA patients whose headaches began between ages 7 and 12 compared to the subjects with MO, while no significant differences were found in the patients whose headaches began after age 12. Conclusions: These findings suggest that elevated serum CGRP is indicative of pediatric migraine, with variations based on migraine type and age of onset. The difference in CGRP in preadolescent migraineurs with and without aura suggest that CGRP levels may vary depending on age and on migraine type.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleDiagnostics
Numberingvol. 14, no. 23, pp. 1-15
p-ISSN2075-4418
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics14232645
URN:NBNurn:nbn:hr:267:236049
Publication2024-11-24
Document URLhttps://www.mdpi.com/2075-4418/14/23/2645
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-12-17 07:01:37