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master's thesis
Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split
Split: University of Split, 2023. urn:nbn:hr:176:620340
Oršolić, Simona
University of Split
University Department of Health Studies

Institutional repository: Repository of the University Department for Health Studies, University of Split

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Oršolić, S. (2023). Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split (Master's thesis). Split: University of Split. Retrieved from https://urn.nsk.hr/urn:nbn:hr:176:620340

Oršolić, Simona. "Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split." Master's thesis, University of Split, 2023. https://urn.nsk.hr/urn:nbn:hr:176:620340

Oršolić, Simona. "Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split." Master's thesis, University of Split, 2023. https://urn.nsk.hr/urn:nbn:hr:176:620340

Oršolić, S. (2023). 'Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split', Master's thesis, University of Split, accessed 17 May 2024, https://urn.nsk.hr/urn:nbn:hr:176:620340

Oršolić S. Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split [Master's thesis]. Split: University of Split; 2023 [cited 2024 May 17] Available at: https://urn.nsk.hr/urn:nbn:hr:176:620340

S. Oršolić, "Potreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split", Master's thesis, University of Split, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:176:620340

Metadata
TitlePotreba i uspješnost mehaničkog čišćenja stolice u djece s Hirschsprungovom bolesti u KBC Split
Title (english)The need and effectiveness of mechanical stool cleaning in children with Hirschsprung's disease at CHC Split
AuthorSimona Oršolić
MentorJakov Meštrović (mentor)
MentorDavor Todorić (sumentor)
Committee memberJakov Meštrović (član povjerenstva)
Committee memberDiana Aranza (predsjednik povjerenstva)
Committee memberAnte Buljubašić (član povjerenstva)
Committee memberDavor Todorić (član povjerenstva)
GranterUniversity of Split
(University Department of Health Studies)
Split
Defense date and country2023-09-25, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Hirschsprungova bolest (HB) je prirođena anomalija inervacije crijeva. Uglavnom je ograničena na kolon te dovodi do potpune ili djelomične opstrukcije u prolasku crijevnog sadržaja. U većine bolesnika, radi se o bolesti kratkog segmenta u kojih je zahvaćen uglavnom rektum i rektosigmoidno područje. Bolest dugog segmenta odnosi se na aganglionozu proksimalno od sigmoidnog kolona dok je potpuna aganglionoza kolona prisutna u rijetkim slučajevima bolesnika te može zahvatiti i tanko crijevo. Mehaničko čišćenje stolice potpomaže smanjivanju distendiranog dijela crijeva što je velika prednost za izvedbu operacije jednog akta. Smanjuje i mogućnost nastanka ozbiljne komplikacije razvoja toksičnog enterokolitisa koje nastaju zbog zadržavanja stolice i umnažanja patogenih bakterija u dilatiranom dijelu crijeva. Cilj istraživanja je utvrditi potrebe i uspješnost mehaničkog čišćenja stolice u djece s dijagnozom HB. Hipoteze istraživanja su da mehaničko čišćenje stolice u djece oboljele od Hirschsprungove bolesti smanjuje duljinu hospitalizacije, primjenu antibiotika te umanjuje broj komplikacija. Istraživanje je provedeno na Klinici za dječju kirurgiju Kliničkog bolničkog centra Split. Podaci su prikupljani putem sekundarnih izvora odnosno putem baze podataka Kliničkog bolničkog centra Split. U istraživanje je uključeno 21 dijete od kojih je ispitivana skupina (n=5) bila podvrgnuta mehaničkom čišćenju stolice. Prikupljeni podaci su statistički obrađeni koristeći Hi kvadrat test, Fisherov egzaktni test, te Mann-Whitney U test. Analiza je napravljena u statističkom softwareu STATISTICA 14, proizvođača TIBCO. Većina djece je bila muškog spola te mlađa od jedne godine. Statistički značajni rezultati uočeni su u broju dana primjene antibiotika (p=0,002), dok u duljini boravka provedenog u bolnici kao i u podacima vezanim za komplikacije nismo pronašli statistički značajne rezultate. HB je rijetka bolest stoga je i ova studija provedena na malom uzorku pacijenata. Potrebno je prikupiti više podataka i u daljnja istraživanja uključiti veći broj bolničkih centara.
Abstract (english)
Hirschsprung`s disease is a congenital anomaly of intestinal inervation. It is mostly limited to colon and leads to complete or partial obstruction and couses problems of passing stool. Majority of patients have a short-segment disease in which the rectum and sigmoid colon are affected. The long segment disease refers to aganglionosis proximal to the sigmoid colon, while complete aganglionosis is present extremly rarely it can it can affect small intestine as well. Mechanical stool cleaning helps to reduce the distended part of the intestine, which is a great advantage for the preformance of a single-stage pulltrough operation. It also reduces the possibility of developing serious complications such as toxic enterocolitis coused by stool retention and multiplication of pathogenic bacteria in the dilated parto f the intestine. Thea im of the research is to determine the needs and effectivenes of mechanical stool cleaning in children with Hirschsprung disease. The reasearch was conducted at the Pediatric Surgery Clinic of University hospital Split Hypotetheses of the research are that mechanical stool cleaning in children with Hirschsprung disease reduces the lenght of hospitalization, use of antibiotics and reduces complications. Dana were collected trought database of the CHC Split. Of 21 children that participated in the research five of them underwent mechanical stool cleaning. Collected dana were statisticaly processed with Chi-square test, Fisher`s exact test and Mann-Whitney U test. Analysis was done in ststatistical software STATISTICA 14, produced by TIBACO. Most of them were male and under one year old. Statisticly sigbificant results were observed in the lenght of antibiotic administration and in the lenght of hospitalisation but there were no significant difference in number of complications between two groups. Hirschsprung disease is rare therefore this study was conducted on a small sample of patients. It is necessary to collect more data and include a larger number of hospital centers in further research.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:176:620340
Study programmeTitle: Nursing (university/graduate)
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2023-09-28 14:06:22