The preconditions for selecting the optimal method are knowing the advantages and reliability of the method and controlling the cycle. Besides the benefit of the method used it is necessary to know the risks, possible complications and undesirable effects for the selected method. The application of oral hormonal contraception is considered one of the major achievements of the medicine in the last century as its application enables free deciding about women's fertility. While at the beginning oral hormonal contraception was used to prevent conception, today its use has gained much wider meaning because apart from contraceptive effect there are also significant non-contraceptive effects. Except as contraceptives, oral hormonal contraceptives are used for therapeutic purposes parallel to the prevention of conception and treatment of disorders of the reproductive age of women. Oral contraceptives are medicine and should be used only after consultation with a doctor. In combination with other medications may be affected by the increased or decreased effect of the contraception itself or the medicine with which it is combined. The role of the midwife is crucial in providing the appropriate knowledge, skills and information for family planning and effective contraception. Midwife achieves a major contribution in preserving women's health by encouraging regular controls, monitoring blood pressure, measuring blood sugar levels, controlling liver enzymes, regular gynecological examinations and acting when a tablet is skipped.