Pain is universal human experience, necessary for protection of organism from damages, it is a physiological symptom which warns us that will appeare or have been appeared pathophysiological processes which can damage the organ or organism. It is always subjective and is defined as the fifth vital sign and therefore we want to emphasize the importance of pain as a symptom. The latest theory of pain is based on the biopsychosocial model, which describes pain as the feeling that is formed by events in the nervous system and organs, individual characteristics, family circumstances and the society and culture of living. The usual division of pain is: physical, mental and physical psychogenic caused pain. Acute postoperative pain is caused by injury on the skin, deep physical or organic structure. It is kind of pain that the patient feels directly after the operation, up to 7 days. Chronic postoperative pain is pain that lasts for more than 3 months after surgery. It is pathological pain that lasts longer than the usual time of healing or treating disease. The treatment of postoperative pain is dependent on the cooperation of several professions. A nurse from the team for the treatment of pain is the first point of contact, while the anesthesiologist and clinical pharmacologist are available as needed. The main role of the nurse is to prevent unnecessary pain to the patient after surgery. The nurses are responsible for noticing pain on a patient, evaluation of pain and the initiation of pain prescribed treatment if necessary, to remove factors that may enhance the pain, to apply non-pharmacological methods of pain relief, avoid the pressure and tension to the painful area, talking to the patient about his fears and alleviate the presence of fear by conversation, re-evaluate and document the patient´s pain changes on a scale of pain. The visual analog scale (VAS) is widely used in the evaluation of postoperative pain. VAS scale is marked at the left end with "no pain" and at the right end is labeled "the strongest pain that you can imagine," seems to exceed the limits of verbal scale. In order to adequately treat the pain, it is necessary to involve the patient in the treatment and control of the pain. Active participation of the patient in the treatment of their own pain, training on methods of pain assessment and pain management techniques affect patient satisfaction and as secondary can have an impact on the intensity of pain. Customer satisfaction leads to internal balance of the individual and may be perceived as an integral component of health. Relaxation is trying to achieve complete physical composure while reducing the metabolism, reduce breathing, lowering of arterial blood pressure, heart rate frequency and such. A balanced (multimodal) analgesia is method of choice whenever possible and is based on the use of NSAIDs and paracetamol for mild pain with opioid analgesics and / or techniques of local anesthesia for moderate and intense pain.