The aim of this study was to investigate the prevalence of anemia among the inhabitants of Split-Dalmatia county from 2003rd to 2012th in primary care and hospitalized patients as well as mortality by regions / offices Split-Dalmatian County. Special attention was paid to anemia due to iron deficiency aged 65 and over compared with R.Hrvatskom. Methods: We used a retrospective comparative epidemiological methods. Statistical analysis was performed in Statistica program 7th were used χ²-test and Student's t-test. Results: In the period 2003rd to 2012th PHC SDŽ highest percentage use of PHC due to anemia due to iron deficiency had children aged 0-6 years 6.83% (95% CI 5.79 to 7.72), followed by children aged 7-19 years 4.45% (95 % CI 3.82 to 4.93), the working age from 20 to 64 years 4.05% (95% CI 3.59 to 4.64) and the smallest percentage of the oldest age 65 years and above 3.31% (95 % CI 3.03 to 3.59). These shares by age for both sexes can be considered as the estimated age prevalence of anemia due to iron deficiency, which for all ages in SDŽ amounts to 4.21% (95% CI 3.99 to 4.47). From hospital discharge was determined sex-age distribution at which higher rates of hospitalization have women in germintivnoj ages and for all ages, while men have higher rates of hospital morbidity at the earliest and oldest age group. For all ages between Croatia and SDŽ no statistical significance of differences, while aged 65 and over SDŽ has a higher average rate of discharge for both sexes. Present trends are the increase in hospitalization rates among women and for both sexes, while males in the fall. The mortality rate of anemia is extremely rare, however, the last few years we can observe an increasing trend in both the anemia due to iron deficiency and anemia due to lack of vitamin B12. Analysis of hospital morbidity in the offices of Split-Dalmatian city of Split shows that a higher rate of discharge than the county average for both sexes aged 65 years and over (257.72 / 100 000), a statistically significant minimum rate of discharge had the town of Hvar (125,76 / 100,000 ). In ženskg sexes aged 65 + most office / area has a trend of increasingly hospital discharge except for women on the islands and Branch Omis. Conclusion: The total balance incidence of anemia due to iron deficiency at all ages and at age 65 years and over a period 2003rd to 2012th years in SDŽ and its areas can be assessed as favorable. At rates of morbidity and mortality SDŽ is like R. Croatia in the middle europskh countries obolježje developed countries. However, the present trend of increasing morbidity and mortality, particularly in women, which is still extremely rare, it is necessary to examine whether the actual prevalence of anemia among the population aged 65 and over.