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undergraduate thesis
Proliferacija neuralnih matičnih stanica u hidrogelovima
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. urn:nbn:hr:159:349781
Tinjić, Mirela
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Tinjić, M. (2015). Proliferacija neuralnih matičnih stanica u hidrogelovima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:349781

Tinjić, Mirela. "Proliferacija neuralnih matičnih stanica u hidrogelovima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. https://urn.nsk.hr/urn:nbn:hr:159:349781

Tinjić, Mirela. "Proliferacija neuralnih matičnih stanica u hidrogelovima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. https://urn.nsk.hr/urn:nbn:hr:159:349781

Tinjić, M. (2015). 'Proliferacija neuralnih matičnih stanica u hidrogelovima', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 29 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:349781

Tinjić M. Proliferacija neuralnih matičnih stanica u hidrogelovima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2015 [cited 2024 November 29] Available at: https://urn.nsk.hr/urn:nbn:hr:159:349781

M. Tinjić, "Proliferacija neuralnih matičnih stanica u hidrogelovima", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:159:349781

Metadata
TitleProliferacija neuralnih matičnih stanica u hidrogelovima
Title (english)Proliferation of neural stem cells in hidrogell
AuthorMirela Tinjić
MentorLidija Šver (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
Zagreb
Defense date and country2015-09-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Interdisciplinary Technical Sciences
Abstract
Matične stanice su trenutno glavna nada za oporavak i obnovu ozljeđenog tkiva mozga. Vrsta matičnih stanica kojima se daje prednost kod ozljeda mozga su neuralne matične stanice. Proučavanje i shvaćanje interakcija između neuralnih matičnih stanica i biomaterijala može unaprijediti opstanak i prožimanje sa ozljeđenim ili oboljelim predjelima središnjeg živčanog sustava. Zbog svoje biokompatibilnosti, hidrofilnog karaktera i mehaničkih svojstava te strukturalne raznolikosti, hidrogelovi se često koriste za regeneraciju živčanog tkiva. Cilj ovoga rada bio je utvrditi da li se metakrilirana gelan guma (MGG) može koristiti kao dobar hidrogelni nosač neuralnih matičnih stanica, što bi joj omogućilo niz primjena u neuroznanosti. Kako bismo to provjerili, uklopili smo mišje neuralne stanice u hidrogelove gelan gume i izmjerili stupanj umnažanja (proliferacije) stanica dva dana nakon uklapanja. Varijacije u preživljenju i drastično opadanje broja stanica je pokazalo da 1%-tni MGG nije pogodan za neuralne matične stanice.
Abstract (english)
Stem cells are currently the main hope for recovery and reconstruction of injured brain tissue. Type of stem cells preferable in brain injury are neural stem cells. The study and understanding of the interactions between neural stem cells and biomaterials can improve survival and fusion with injured or diseased areas of the central nervous system. Because of its biocompatibility, the hydrophilic character, the mechanical properties and structural diversity, hydrogels are widely used for regeneration of nerve tissue. The aim of this research is to examine whether methacrylated gellan gum (MGG) can be used as a good hydrogel carrier of neural stem cells, which would provide a range of possibilities of applications in neuroscience. To test this, we match mice neural cells in hydrogel gellan gum and measure the degree of multiplication (proliferation) cells five days after switching. Variations in survival and declining cells showed that 1% MGG is not suitable for neural stem cells.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:349781
Study programmeTitle: Nutrition
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2015-12-14 12:59:58