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undergraduate thesis
Peptidomimetici kao terapeutici
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. urn:nbn:hr:159:359119
Radić, Ivana
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Radić, I. (2016). Peptidomimetici kao terapeutici (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:359119

Radić, Ivana. "Peptidomimetici kao terapeutici." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:359119

Radić, Ivana. "Peptidomimetici kao terapeutici." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:359119

Radić, I. (2016). 'Peptidomimetici kao terapeutici', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 30 December 2024, https://urn.nsk.hr/urn:nbn:hr:159:359119

Radić I. Peptidomimetici kao terapeutici [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2016 [cited 2024 December 30] Available at: https://urn.nsk.hr/urn:nbn:hr:159:359119

I. Radić, "Peptidomimetici kao terapeutici", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:159:359119

Metadata
TitlePeptidomimetici kao terapeutici
Title (english)Peptidomimetics as therapeutics
AuthorIvana Radić
MentorLidija Barišić (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2016-06-30, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Peptidi nisu pogodni za korištenje u terapeutske svrhe iz brojnih razloga. U cilju poboljšanja nepovoljnih svojstava njihove se strukture modificiraju, a nastali spojevi nazivaju se peptidomimetici. Oni oponašaju strukturu i biološki učinak peptida te se mogu koristiti kao lijekovi. Autoimune bolesti posljedica su nemogućnosti razlikovanja vlastitih stanica od stranih antigena pri čemu organizam uništava vlastito tkivo. U terapiji autoimunih bolesti koriste se imunomodulatori. Multipla skleroza autioimuna je bolest kod koje se razara mijelin unutar središnjeg živčanog sustava što rezultira nizom simptoma. Mimetici peptidnih epitopa, supresijom razgradnje mijelina, uspješno se koriste u liječenju multiple skleroze. Liječenju karcinoma pristupa se antigen-specifičnom imunoterapijom čiji je cilj omogućiti stanicama imunosustava prepoznavanje tumorskih stanica i selektivno uništavanje.
Abstract (english)
The peptides are not suitable for therapeutic application for various reasons. Their structures are modified to improve the unfavorable properties and the resulting compounds are named peptidomimetics. They mimic the structure and biological effect of the peptides and can be used as medicaments. Autoimmune diseases are the result of inability to distinguish its own cells from foreign antigens in which the body destroys its own tissue. The immunomodulators are employed in the treatment of autoimmune diseases. Multiple sclerosis is an autoimmune disease that destroys myelin within the central nervous system resulting in a set of symptoms. The protein epitope mimetics are successfully applied in treatment of multiple sclerosis owing to their role in the suppression of degradation of myelin. One of the cancer treatment approaches is based on the antigen-specific immunotherapy, which aims to enable the cells of the immune system to recognise and selectively destroy the tumor cells.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:359119
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-24 10:17:38