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undergraduate thesis
Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. urn:nbn:hr:159:931838
Svrze, Karlo
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Svrze, K. (2016). Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:931838

Svrze, Karlo. "Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:931838

Svrze, Karlo. "Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:931838

Svrze, K. (2016). 'Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 29 June 2024, https://urn.nsk.hr/urn:nbn:hr:159:931838

Svrze K. Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2016 [cited 2024 June 29] Available at: https://urn.nsk.hr/urn:nbn:hr:159:931838

K. Svrze, "Utjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:159:931838

Metadata
TitleUtjecaj deprotonirajućeg agensa na tijek reakcije kopulacije ferocena na adenin
Title (english)Influence of deprotonating agent on the course of coupling reaction of ferrocene with adenine
AuthorKarlo Svrze
MentorSenka Djaković (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2016-06-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Analozi nukleozida, među kojima i kopulati nukleobaza s ferocenskim derivatom, pokazuju značajno biološko djelovanje te su stoga važno područje istraživanja. Uz svoje biološko djelovanje, analozi također pokazuju i zanimljiva elektrokemijska svojstva. Cilj ovog završnog rada je ispitati reaktivnost NaH kao deprotonirajućeg agensa na regioselektivnost reakcija priprave kopulata ferocenskog derivata i nukleobaze adenina s karbonilnom podjedinicom kao poveznicom. Posebna pozornost posvećena je vremenu deproktecije, kao jednom od faktora koji može utjecati na usmjerenje reakcije prema nastajanju N9-ferocenoil-adenina. Struktura pripravljenih spojeva potvrđene je IR i NMR spektroskopijom.
Abstract (english)
Ferrocene modified nucleobases are nucleoside analogues that represent an important scientific research field. They possess significant biological activity and electrochemical potential. The main goal of this final work was to test reactivity of deprotonating agent NaH on the regioselectivity of chemical reaction considering the time of deprotection as one of the factors that direct reaction towards N9-ferocenoyl formation. Chemical reaction includes preparation of adenine derivate of ferrocene linked with carbonyl subunit. Structure of prepared compounds was confirmed using IR- and NMR- spectroscopy
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:931838
Study programmeTitle: Food Technology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-24 12:03:29