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master's thesis
Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. urn:nbn:hr:159:875443
Sulimanec, Antonija
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control
Laboratory for Nutrition Science

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Sulimanec, A. (2010). Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:875443

Sulimanec, Antonija. "Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:875443

Sulimanec, Antonija. "Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:875443

Sulimanec, A. (2010). 'Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:875443

Sulimanec A. Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2010 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:159:875443

A. Sulimanec, "Međudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:159:875443

Metadata
TitleMeđudjelovanje kadmija i esencijalnih mikroelemenata željeza i cinka u neskotnih i skotnih pokusnih štakorica
Title (english)Interaction of cadmium and essential microelements iron and zinc in non-pregnant and pregnant laboratory rats
AuthorAntonija Sulimanec
MentorMartina Piasek (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
(Laboratory for Nutrition Science)
Zagreb
Defense date and country2010-11-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Svrha rada bila je procijeniti učinke peroralne izloženosti kadmiju (50 ppm Cd u obliku klorida u piću) u štakorica izvan i tijekom graviditeta na razdiobu kadmija i esencijalnih mikroelemenata željeza i cinka u odraslih štakorica i fetusima. Izloženost je trajala tijekom 20 dana odnosno od 1. do 20. dana skotnosti. Mikrolementi u krvi, jetri i bubregu štakorica te u posteljicama i fetusima analizirani su atomskom apsorpcijskom spektrometrijom. U skotnih u odnosu na neskotne izložene štakorice bila su izraženija povećanja kadmija u krvi i unutarnjim organima te jača smanjenja željeza u jetri i bubrezima. Cink se povećao u jetri svih izloženih ženki, a smanjio u bubrezima skotnih izloženih štakorica. Nakupljanje kadmija u posteljici bilo je povezano sa smanjenjima cinka u posteljici i željeza u fetusima. U zaključku, supkronična izloženost kadmiju tijekom graviditeta remeti tkivne esencijalne mikroelemente jače nego izvan graviditeta i ometa njihov prijenos posteljicom do fetusa.
Abstract (english)
The work aimed at assessing effects of oral cadmium exposure (50 ppm Cd as chloride in drink) in female rats out of and during pregnancy on cadmium and essential microelements iron and zinc distribution in adult rats and foetuses. Exposure lasted throughout 20 days or from day 1-20 of gestation. Microelements in rat blood, liver and kidney, and in placenta and foetuses were analysed by atomic absorption spectrometry. In pregnant in comparison to non-pregnant exposed rats were more pronounced both cadmium increases in blood and internal organs and iron decreases in the liver and kidney. In exposed rats, liver zinc increased in all, and kidney zinc decreased in pregnant rats. Cadmium accumulation in placenta was associated with decreases of placental zinc and foetal iron. In conclusion, cadmium exposure during pregnancy causes more perturbations in essential microelements in tissues than out of pregnancy, and disrupts their placental transport to the foetus.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:875443
Study programmeTitle: Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2017-08-29 11:50:14