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undergraduate thesis
Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2017. urn:nbn:hr:159:925122
Ivanić, Ana
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Ivanić, A. (2017). Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:925122

Ivanić, Ana. "Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2017. https://urn.nsk.hr/urn:nbn:hr:159:925122

Ivanić, Ana. "Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2017. https://urn.nsk.hr/urn:nbn:hr:159:925122

Ivanić, A. (2017). 'Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 17 July 2024, https://urn.nsk.hr/urn:nbn:hr:159:925122

Ivanić A. Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2017 [cited 2024 July 17] Available at: https://urn.nsk.hr/urn:nbn:hr:159:925122

A. Ivanić, "Priprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:159:925122

Metadata
TitlePriprava biološki aktivnog konjugata ferocena i o-kinolina povezanih 1,2,3-triazolnom poveznicom
Title (english)Preparation of biologically active ferrocene and o-quinoline conjugate joined with 1,2,3-triazole connection
AuthorAna Ivanić
MentorJasmina Lapić (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2017-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Ferocen je spoj koji pokazuje iznimnu stabilnost zbog svojeg aromatičnog karaktera i ima bitnu ulogu u suvremenoj medicini jer posjeduje jedinstvena svojstva kao što su netoksičnost i stabilnost pri fiziološkim uvjetima. Derivati ferocena pokazuju široku primjenu u kliničkim ispitivanjima. U ovom radu je opisana sinteza potencijalno biološki aktiviranog konjugata ferocena i O-kinolina povezanih 1,2,3-triazolnom poveznicom koja je provedena klasičnom reakcijom "klik kemije", 1,3-dipolarnom cikloadicijom O-alkin kinolina i ferocenskog azida uz prisutnost bakra kao katalizatora. Struktura priređenih spojeva potvrđena je IR i NMR spektroskopijom.
Abstract (english)
Ferrocene is a chemical compound that exhibits exceptional stability due to its aromatic character. It holds an important role in modern medicine given its unique properties as nontoxicity and stability amid physiological conditions. Ferrocene derivatives are displaying widespread use in clinical testing. In this paper it has been described the synthesis of the potentially biologically activated conjugate of ferrocene with O-quinoline joined 1,2,3,-triazole connection vis-a-vis classic reaction "click chemistry", 1,3-dipolar cycloaddition of O-alkyne quinoline and ferrocene azide with copper as a catalyst. Structures of synhtesized compounds were validated by IR and NMR spectroscopic analysis.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:925122
Study programmeTitle: Food Technology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2017-09-25 10:56:36