prikaz prve stranice dokumenta Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije
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doctoral thesis
Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. urn:nbn:hr:159:011277
Keser, Irena
University of Zagreb
Faculty of Food Technology and Biotechnology

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Keser, I. (2010). Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:011277

Keser, Irena. "Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:011277

Keser, Irena. "Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:011277

Keser, I. (2010). 'Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 27 December 2024, https://urn.nsk.hr/urn:nbn:hr:159:011277

Keser I. Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2010 [cited 2024 December 27] Available at: https://urn.nsk.hr/urn:nbn:hr:159:011277

I. Keser, "Povezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:159:011277

Metadata
TitlePovezanost razina serumskog folata, vitamina b12 i homocisteina s mineralnom gustoćom kosti u starije ženske populacije
Title (english)Association of serum folate, vitamin b12 and homocysteine levels with bone mineral density in elderly women
AuthorIrena Keser
MBZ: 266856
MentorIrena Colić Barić (mentor)
MBZ: 120646
Committee memberVladimir Mrša (predsjednik povjerenstva)
MBZ: 39525
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
Zagreb
Defense date and country2010-12-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Universal decimal classification
(UDC)		577 - Biochemistry. Molecular biology. Biophysics
Abstract
Povišena razina homocisteina se smatra novim rizičnim čimbenikom za osteoporozu. Primarni cilj ovog istraživanja je bio utvrditi interventnom duplo slijepom placebo kontroliranom studijom postoji li utjecaj folne kiseline i vitamina B12 na markere koštane pregradnje. Sekundarni cilj je bio utvrditi postoji li moguća povezanost razina folata, vitamina B12 i homocisteina s mineralnom gustoćom kosti (BMD) u žena starije dobi. U interventnoj studiji je sudjelovala 31 žena od ukupno 105 žena dobi 65-93 godine koje su obuhvaćene ovim istraživanjem. Interventnom studijom je utvrđen pozitivan utjecaj folne kiseline i vitamina B12 na razinu homocisteina, dok nije utvrđen utjecaj na razine markera koštane pregradnje (alkalna fosfataza i CTx). Utvrđena je negativna korelacija (p<0,05) razine homocisteina s BMD-om vrata femura te pozitivna korelacija (p<0,05) razine vitamina B12 s BMD-om vrata femura.
Abstract (english)
Elevated homocysteine level is newly recognized risk factor for osteoporosis. Primary aim of this study was to determine whether there is an impact of folic acid and vitamin B12 on bone turnover markers by an intervention double blind placebo controlled study. Secondary aim of the study was to determine possible association of folate, vitamin B12 and homocysteine levels with bone mineral density (BMD) in elderly women. In the intervention study subjects were 31 of total 105 women 65 to 93 years of age. The results of the intervention study have showed a positive impact of folic acid and vitamin B12 on homocysteine level while the impact on bone turnover marker levels (alkaline phosphatase and CTx) was not determined. Negative correlation (p<0,05) was determined for homocysteine and femoral neck BMD, and positive correlation (p<0,05) for vitamin B12 level and femoral neck BMD.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:011277
Promotion2011-07-03
Study programmeTitle: Nutrition
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor znanosti/doktorica znanosti (doktor znanosti/doktorica znanosti)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2018-05-15 11:10:07