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undergraduate thesis
Hepatoprotektivni učinak aronije u c57bl miša
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. urn:nbn:hr:159:197838
Vučinić, Valentina
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Vučinić, V. (2015). Hepatoprotektivni učinak aronije u c57bl miša (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:197838

Vučinić, Valentina. "Hepatoprotektivni učinak aronije u c57bl miša." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. https://urn.nsk.hr/urn:nbn:hr:159:197838

Vučinić, Valentina. "Hepatoprotektivni učinak aronije u c57bl miša." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2015. https://urn.nsk.hr/urn:nbn:hr:159:197838

Vučinić, V. (2015). 'Hepatoprotektivni učinak aronije u c57bl miša', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 05 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:197838

Vučinić V. Hepatoprotektivni učinak aronije u c57bl miša [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2015 [cited 2024 November 05] Available at: https://urn.nsk.hr/urn:nbn:hr:159:197838

V. Vučinić, "Hepatoprotektivni učinak aronije u c57bl miša", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:159:197838

Metadata
TitleHepatoprotektivni učinak aronije u c57bl miša
Title (english)Hepatoprotective effect of aronia in mouseC57BL
AuthorValentina Vučinić
MentorIrena Landeka Jurčević (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
Zagreb
Defense date and country2015-09-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Food Chemistry and Biochemistry
Abstract
Aronia melanocarpa je voće bogato fenolnim spojevima - uglavnom flavonoidima iz podrazreda antocijana. Antocijani su u vodi topljivi biljni pigmenti s antioksidacijskim, protuupalnim, antimikrobnim, hepatoprotektivnim i gastroprotektivnim svojstvima. Proučavali smo učinak praha A. melanocarpa (PAM) u miša sa 2%-tnim kolesterolom izazvanom hiperkolesterolemijom. PAM (1 g/kg/dan) je primjenjen oralno. Malondialdehid (MDA), superoxide dismutaza (SOD), reducirani glutation (GSH) i oksidirani glutation (GSSG) određeni su u jetri miša i korišteni kao biokemijski markeri oksidacijskog stresa. Primjena kolesterola izazvala je lipidnu peroksidaciju u jetri (izmjereno preko malondialdehida - MDA) i iscrpljivanje reduciranog glutationa (GSH). U usporedbi s kontrolom, SOD i GSH znatno su povećani (p <0,05) u grupi miševa koji su tretirani sa prahom aronije.
Abstract (english)
Aronia melanocarpa fruits are rich in phenolic substances—mainly flavonoids from the anthocyanin subclass. The anthocyanins are water-soluble plant pigments with antioxidant, anti-inflammatory, antimicrobial, hepatoprotective, gastroprotective and other activities. We studied the effect of A. melanocarpa powder (PAM) on on 2% cholesterol induced hypercholesterolemia in mice. PAM (1 g/kg/day) was applied orally. Malondialdehyde (MDA), supeoxide dismutase and also reduced glutathione (GSH) and oxidized glutathione (GSSG) in mouse liver were determined and used as biochemical markers of the oxidative status. The administration of cholesterol increased liver lipid peroxidation (as measured by malondialdehyde - MDA) and caused a depletion of liver reduced glutathione (GSH). Compared with the control, SOD and GSH were significantly increased (p <0.05) in the group of mice treated with powder chokeberry.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:197838
Study programmeTitle: Nutrition
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2015-12-14 09:49:38