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master's thesis
Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. urn:nbn:hr:159:909030
Fiolić, Iva
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Cell Technology, Application and Biotransformations

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Fiolić, I. (2016). Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:909030

Fiolić, Iva. "Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:909030

Fiolić, Iva. "Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2016. https://urn.nsk.hr/urn:nbn:hr:159:909030

Fiolić, I. (2016). 'Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:909030

Fiolić I. Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2016 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:159:909030

I. Fiolić, "Priprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:159:909030

Metadata
TitlePriprava i ekotoksikološka karakterizacija prirodnih eutektičnih otapala
Title (english)Preparation and ecotoxicological characterization of natural deep eutectic solvent
AuthorIva Fiolić
MentorKristina Radošević (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Cell Technology, Application and Biotransformations)
Zagreb
Defense date and country2016-09-26, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Prirodna eutektična otapala definiraju se kao smjese akceptora i donora vodikove veze čija temperatura tališta je mnogo niža od temperature tališta pojedinačnih komponenata smjese. Posjeduju slična fizikalno-kemijska svojstva kao tradicionalne ionske kapljevine, ali su mnogo jeftinija i ekološki prihvatljivija. Zbog mogućnosti priprave prirodnih eutektičnih otapala iz velikog broja različitih ishodnih tvari moguće je prilagoditi njihova svojstva željenoj primjeni. U ovom radu pripravljeno je osam eutektičnih otapala u različitim molarnim omjerima (kolin klorid: sorbitol, kolin klorid: ksilitol, limunska kiselina: prolin, limunska kiselina: glukoza, jabučna kiselina: glukoza, betain: glukoza, betain: jabučna kiselina: prolin, betain: jabučna kiselina:glukoza) i ispitan je njihov utjecaj na preživljenje HeLa i HEK293T humane stanične linije te je izmjeren antioksidacijski kapacitet pet otapala ORAC metodom. Na temelju dobivenih rezultata možemo zaključiti da ispitana prirodna eutektična otapala nemaju inhibitorni učinak na stanične linije te posjeduju antioksidacijska svojstva.
Abstract (english)
Natural deep eutectic solvents are defined as mixture of acceptor and hydrogen bond donor whose melting temperature is much lower than the melting temperatureof the individual components of the mixture. They possess similar physical and chemical properties as traditional ionic liquids, but they are much cheaper and environmentally friendly. Due to the possibility of formation natural deep eutectic solvents from a wide range of individual compounds it is possible to adjust their properties to particular application. In this study, eight eutectic deep solvents were prepared in different molar ratios (choline chloride: sorbitol, choline chlorid: xylitol, citric acid: proline, citric acid: glucose, malic acid: glucose, betaine: glucose, betaine: malic acid: proline, betaine: malic acid: glucose) and examined their effect on survival of HeLa and HEK293T human cell lines. Also, the antioxidant capacity of five natural deep eutectic solvents was measured by ORAC method. Based on the results, we can conclude that examined natural deep eutectic solvents have no inhibitory effect on the cell lines and possess antioxidant properties.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:909030
Study programmeTitle: Molecular Biotechnology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka molekularne biotehnologije (magistar/magistra inženjer/inženjerka molekularne biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-26 08:17:05