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master's thesis
Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2019. urn:nbn:hr:159:928203
Čengić, Lea
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control
Laboratory for Nutrition Science

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Čengić, L. (2019). Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:928203

Čengić, Lea. "Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2019. https://urn.nsk.hr/urn:nbn:hr:159:928203

Čengić, Lea. "Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2019. https://urn.nsk.hr/urn:nbn:hr:159:928203

Čengić, L. (2019). 'Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 23 July 2024, https://urn.nsk.hr/urn:nbn:hr:159:928203

Čengić L. Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2019 [cited 2024 July 23] Available at: https://urn.nsk.hr/urn:nbn:hr:159:928203

L. Čengić, "Sastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:159:928203

Metadata
TitleSastav tijela i potrošnja energije u mirovanju bolesnika s upalnim bolestima crijeva na biološkoj terapiji
Title (english)Body composition and resting energy expenditure in patients with inflammatory bowel disease receiving biological therapy
AuthorLea Čengić
MentorDarija Vranešić Bender (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
(Laboratory for Nutrition Science)
Zagreb
Defense date and country2019-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Abstract
Crohnova bolest (CB) i ulcerozni kolitis (UK) dva su glavna oblika upalnih bolesti crijeva, a terapija biološkim lijekovima pokazala se najučinkovitijom za kontrolu simptoma i postizanje kliničke remisije. Cilj ovoga rada bio je odrediti sastav tijela te potrošnju energije u mirovanju bolesnika koji se liječe biološkom terapijom. Provedeno istraživanje obuhvatilo je 74 ambulantna pacijenta Kliničkog bolničkog centra Zagreb (52 ispitanika iz CB skupine te 22 ispitanika iz UK skupine). Metodom bioelektrične impedancije dobiveni su podaci o sastavu tijela ispitanika – tjelesna masa (TM), indeks tjelesne mase (ITM), udio masnog tkiva (%MT), visceralno masno tkivo (VMT) te mišićna masa (MM). Kod 32% ispitanika zabilježen je povećani ITM, dok 46% ispitanika ima povišen %MT. Indeksom skeletnog mišićja (SMI) utvrđena je prisutnost umjerene sarkopenije kod 32 ispitanika, od čega je bilo 30 muškaraca, χ2=38,11, p<0,00001. Metodom indirektne kalorimetrije (IC) dobivene su vrijednosti potrošnje energije u mirovanju (RMR), pri čemu je izmjerena RMR (1570 kcal) prosječno značajno niža od predviđene (1640 kcal), t(73)=-3,023, p<0,05. Rezultatima ovog istraživanja kod ispitanika je utvrđena značajna zastupljenost umjerene sarkopenije, povišena tjelesna i masna masa te blago snižena potrošnja energije u mirovanju, što se može povezati s utjecajem biološke terapije.
Abstract (english)
Crohn’s disease (CD) and ulcerative colitis (UC) are the two major forms of inflammatory bowel disease and biological therapy has proven to be the most effective in controlling the symptoms and inducing clinical remission. The aim of this study was to determine body composition and resting energy expenditure of patients treated with biological therapy. The study includes 74 patients at the Clinical Hospital Center Zagreb (52 patients from the CD group and 22 from the UC group). The bioelectrical impedance method obtained data on the body composition of the subjects – body mass (BM), body mass index (BMI), fat mass (FM), visceral fat rating (VFR) and muscle mass (MM). Increased BMI was observed in 32% of the patients, while 46% of them had an increased FM. The skeletal muscle index (SMI) identified the presence of moderate sarcopenia in 32 patients, of which 30 were men, χ2=38,11, p<0,00001. Indirect calorimetry (IC) obtained the value of resting energy expenditure (REE), with the measured REE (1570 kcal) on average significantly lower than predicted (1640 kcal), t(73)=-3,023, p<0,05. The results of this study revealed a significant prevalence of moderate sarcopenia, increased body mass and fat mass, and slightly lowered resting energy expenditure, which may be related to the impact of biological therapy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:928203
Study programmeTitle: Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2019-12-30 10:37:21