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undergraduate thesis
Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. urn:nbn:hr:159:532347
Begić, Darija
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Antibiotic, Enzyme, Probiotic and Starter Cultures Technology

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Begić, D. (2020). Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:532347

Begić, Darija. "Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:532347

Begić, Darija. "Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:532347

Begić, D. (2020). 'Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 05 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:532347

Begić D. Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2020 [cited 2024 November 05] Available at: https://urn.nsk.hr/urn:nbn:hr:159:532347

D. Begić, "Egzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:159:532347

Metadata
TitleEgzopolisaharidi kao funkcionalne biomolekule probiotičkih bakterija
Title (english)Exopolysaccharides as functional biomolecules of the probiotic bacteria
AuthorDarija Begić
MentorJasna Novak (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Antibiotic, Enzyme, Probiotic and Starter Cultures Technology)
Zagreb
Defense date and country2020-09-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Bakterije mliječne kiseline (BMK) sintetiziraju spektar polisaharida koji se odlikuju raznolikošću u strukturi, sastavu gradivnih podjedinica i mehanizmom biosinteze. Zbog svojih fizikalno-kemijskih svojstava ovi polimeri se industrijski primjenjuju za poboljšanje teksture i senzorskih svojstava fermentiranih proizvoda. No osim doprinosa tehnološkim aspektima, egzopolisharidi BMK imaju funkciju zaštitnog sloja koji određuje i karakteristike površine bakterijske stanice, a značajni su za preživljavanje probiotičkih sojeva prilikom prolaska kroz gastrointestinalni trakt (GIT) domaćina. Pretpostavlja se da ove površinske biomolekule posreduju prilikom interakcija bakterijske stanice s mikrookolišem, a istražuje se potencijalna biološka uloga u imunomodulaciji, antioksidativnom, antimikrobnom, čak antitumorskom djelovanju probiotičkih bakterija. Zbog specifične kemijske strukture ne razgrađuju se u GIT, te u kolonu domaćina mogu biti izvor supstrata za korisne bakterijske vrste iz roda Bifidobacterium gdje selektivno potiču njihov rast i tako posreduju u modulaciji sastava intestinalne mikrobiote. U kolonu mogu biti izvor ugljika i za druge predstavnike intestinalne mikrobiote koji ih fermentiraju do kratkolančanih masnih kiselina (engl. short-chain fatty acids; SCFA) poput butirata, propionata i acetata koje su značajne u snabdjevanju energije stanica intestinalnog epitela, modulaciji metaboličkih puteva, inhibiciji intestinalnih patogena i imunomodulaciji.
Abstract (english)
Lactic acid bacteria (LAB) synthesize a spectrum of polysaccharides characterized by diversity in structure, the composition of repeating units and mechanism of biosynthesis. Due to their physical-chemical properties, these polymers have an industrial application to improve the texture and sensory properties of fermented products. In addition to contributing to technological aspects, LAB exopolysaccharides have the function of a protective layer that determines the characteristics of the bacterial cell surface and promote the survival of probiotic strains in the gastrointestinal tract (GIT) of the host. These surface biomolecules mediate bacterial cell-microenvironment interactions. Their potential roles in immune response, antioxidant, antimicrobial, and even antitumor activities of probiotic bacteria are investigated. Due to their specific chemical structure, exopolysaccharides are not digested in the upper GIT, and in the colon can be a source of substrates for beneficial Bifidobacterium strains and also can be utilized by other specific beneficial members of the gut microbiota with the influence on intestinal microbiota composition. In colon some representatives of the intestinal microbiota ferment them to short-chain fatty acids (SCFA) such as butyrate, propionate and acetate, which are important in supplying energy to intestinal epithelial cells, modulating metabolic pathways, inhibition of intestinal pathogens and immune response.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:532347
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2020-10-22 12:50:29