prikaz prve stranice dokumenta Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija
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master's thesis
Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. urn:nbn:hr:159:647177
Stanečić, Željka
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Biology and Microbial Genetics

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Stanečić, Ž. (2020). Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:647177

Stanečić, Željka. "Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:647177

Stanečić, Željka. "Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:647177

Stanečić, Ž. (2020). 'Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 09 June 2024, https://urn.nsk.hr/urn:nbn:hr:159:647177

Stanečić Ž. Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2020 [cited 2024 June 09] Available at: https://urn.nsk.hr/urn:nbn:hr:159:647177

Ž. Stanečić, "Biološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:159:647177

Metadata
TitleBiološki učinak polifenola iz mahune graška i ljuske luka kao sekundarnih izvora fitokemikalija
Title (english)Biological effect of polyphenols from pea peel and onion skin as a secondary source of phytochemicals
AuthorŽeljka Stanečić
MentorKsenija Durgo (mentor)
Committee memberDraženka Komes (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Biology and Microbial Genetics)
Zagreb
Defense date and country2020-11-25, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Prehrambena industrija proizvodi veliku količinu otpadne biomase koja predstavlja ekološki rizik, stoga se danas intenzivno istražuju novi načini valorizacije otpadnih materijala. Nusproizvodi poput mahune graška i ljuske luka nedovoljno su iskorišteni izvori bioaktivnih spojeva, među kojima se ističu polifenoli, sekundarni biljni metaboliti koji posjeduju visok antioksidacijski potencijal te pružaju značajnu zaštitu od razvoja raznih kroničnih bolesti. Cilj rada je istražiti biološki učinak ekstrakata mahune graška i ljuske luka na stanične makromolekule te humane stanične linije karcinoma epitela usne šupljine Cal27 i hepatocelularnog karcinoma jetre HepG2 u koncentracijama pri kojima se ovi spojevi mogu naći u realnim uvjetima u probavnom sustavu čovjeka. Rezultati su pokazali da polifenoli sadržani u mahuni graška djeluju protektivno na stanične makromolekule sprečavajući štetne učinke UV zračenja i slobodnih radikala na genetički materijal te oksidacijske promjene na proteinima i lipidima, dok je ljuska luka bogata polifenolima koji u određenim uvjetima mogu ispoljiti prooksidacijsko i genotoksično djelovanje
Abstract (english)
The food industry produces a large amount of waste biomass that poses as an environmental risk, hence today new ways of valorizing waste materials are being intensively researched. By-products such as pea peel and onion skin are underutilized sources of bioactive compounds, such as polyphenols, secondary plant metabolites that have high antioxidant potential and provide significant protection against the development of various chronic diseases. The aim of this study is to determine the biological effect of pea peel and onion skin extracts on cellular macromolecules, human oral epithelial carcinoma cell line Cal27 and hepatocellular liver carcinoma cell line HepG2 in concentrations at which these compounds can be found in the human digestive system. The results showed that polyphenols contained in the pea peel have a protective effect on cellular macromolecules by preventing the harmful effects of UV radiation and free radicals on genetic material and oxidative changes on proteins and lipids, while onion skin is rich in polyphenols that can exert prooxidative and genotoxic effects.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:647177
Study programmeTitle: Molecular Biotechnology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka molekularne biotehnologije (magistar/magistra inženjer/inženjerka molekularne biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2020-12-08 14:06:05