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master's thesis
Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. urn:nbn:hr:159:372291
Pinčar, Ana
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Food Quality Control
Laboratory for Food Quality Control

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Pinčar, A. (2020). Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:372291

Pinčar, Ana. "Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:372291

Pinčar, Ana. "Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2020. https://urn.nsk.hr/urn:nbn:hr:159:372291

Pinčar, A. (2020). 'Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 28 March 2025, https://urn.nsk.hr/urn:nbn:hr:159:372291

Pinčar A. Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2020 [cited 2025 March 28] Available at: https://urn.nsk.hr/urn:nbn:hr:159:372291

A. Pinčar, "Razvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:159:372291

Metadata
TitleRazvoj metode za određivanje makrolida, tetraciklina i sulfonamida u medu metodom tekućinske kromatografije s masenom detekcijom
Title (english)Method development for detection of macrolides, tetracyclines and sulfonamides in honey with liquid chromatography with mass detection
AuthorAna Pinčar
MentorMirjana Hruškar (mentor)
Committee memberBlaženka Kos (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Food Quality Control)
(Laboratory for Food Quality Control)
Zagreb
Defense date and country2020-09-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Sve veća prisutnost antibiotika u humanoj, ali i veterinarskoj medicini, dovela je do potrebnih mjera kojima se rezidue antibiotika moraju kontrolirati posebice u matriksima kao što je hrana jer predstavljaju izravnu prijetnju zdravlju potrošača. Od toga nije izuzet ni med kao prehrambeni proizvod izrazitog nutritivnog sastava, a za kojeg nema definiranih NDK (najmanja dopuštena količina) vrijednosti. Najzastupljeniji antibiotici u medu pokazali su se makrolidi, tetraciklini te sulfonamidi te je stoga posvećena pozornost njima u ovome radu, pri čemu je proveden razvoj metode prikladne za istovremeno određivanje svih već spomenutih vrsta antibiotika. Eksperimentom je utvđeno da je metoda tekućinske kromatografije sa masenom spektrometrijom (LC-MS/MS) prikladna za određivanje analita iz skupine makrolida, tetraciklina i sulfonamida.
Abstract (english)
Wide usage of antibiotics in human and veterinary medicine brought more focus on monitoring of antibiotic residues in matrices as food due to potential risk for consumer’s health. Honey, with a range of nutritional value, is also being monitored despite no MRL (maximum residue levels) were established. Macrolides, tetracyclines and sulfonamides are most common antibiotics in honey, therefore the focus in this experiment was to develop a method suitable for detection of all the antibiotics above. After performed experiment, it is determined that liquid chromatography with mass spectrometry (LC-MS/MS) is suitable method for multiclass determination of analytes from group of macrolides, tetracyclines and sulfonamides.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:372291
Study programmeTitle: Food Safety Management
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane (magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2021-01-20 11:24:39