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undergraduate thesis
Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2021. urn:nbn:hr:159:419932
Vrabec, Anamarija
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Physical Chemistry and Corrosion

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Vrabec, A. (2021). Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:419932

Vrabec, Anamarija. "Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2021. https://urn.nsk.hr/urn:nbn:hr:159:419932

Vrabec, Anamarija. "Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2021. https://urn.nsk.hr/urn:nbn:hr:159:419932

Vrabec, A. (2021). 'Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 14 January 2025, https://urn.nsk.hr/urn:nbn:hr:159:419932

Vrabec A. Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2021 [cited 2025 January 14] Available at: https://urn.nsk.hr/urn:nbn:hr:159:419932

A. Vrabec, "Primjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:159:419932

Metadata
TitlePrimjena spektrometrije masa u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari
Title (english)Mass spectrometric analysis of illegal pharmaceutical adulterants in botanical dietary supplements and herbal remedies
AuthorAnamarija Vrabec
MentorAnita Horvatić (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Physical Chemistry and Corrosion)
Zagreb
Defense date and country2021-09-01, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Zbog sve veće potražnje za biljnim dodacima prehrani, kao i biljnim lijekovima, porastao je i broj njihovih ilegalnih, neodobrenih te zabranjenih sastojaka, kao što su inhibitori fosforodiesteraze tipa 5 (PDE-5), anabolički steroidi te hipoglikemična i antihipertenzivna sredstva. Interakcija s drugim lijekovima te prekomjerna i nepravilna upotreba mogu uzrokovati nuspojave kao što su srčani ili moždani udar, halucinacije, tahikardija, povraćanje, grčevi i uzrujanost. Praćenjem proizvodnje i razvoja biljnih pripravaka žele se zaštiti zdravlje i sigurnost potrošača. Neke od metoda koje se koriste u kontroli kvalitete ovih proizvoda su tekućinska kromatografija-spektrometrija masa (LC-MS) i plinska kromatografija-spektrometrija masa (GC-MS). Ovaj rad će se pobliže dotaknuti same tehnike spektrometrije masa (MS) kao i njene primjene u analizi biljnih pripravaka s ciljem pronalaska ilegalnih farmaceutski aktivnih tvari.
Abstract (english)
Due to the high demand for botanical dietary supplements and herbal remedies, there is an increase in illegal, unapproved and prohibited ingredients such as phosphodiesterase type 5 (PDE-5) inhibitors, anabolic steroids, hypoglycemic and antihypertensive agents adulterated within these products. Interaction with other medications, overuse and misuse can lead to serious side effects, such as heart attack, hallucinations, tachycardia, vomiting, convulsions, agitation and seizures. Monitoring the development of these products will ensure the health and safety of consumers. Some of the analytical techniques used for the aforementioned monitoring are liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC–MS). This thesis will address mass spectrometry (MS) and its application in the analysis of botanical dietary supplements and herbal remedies in order to detect illegal pharmaceutical adulterants.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:419932
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2021-09-27 09:55:32