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undergraduate thesis
Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. urn:nbn:hr:159:156273
Paradžik, Katarina
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Organic Chemistry

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Paradžik, K. (2023). Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:156273

Paradžik, Katarina. "Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. https://urn.nsk.hr/urn:nbn:hr:159:156273

Paradžik, Katarina. "Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. https://urn.nsk.hr/urn:nbn:hr:159:156273

Paradžik, K. (2023). 'Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 17 July 2024, https://urn.nsk.hr/urn:nbn:hr:159:156273

Paradžik K. Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2023 [cited 2024 July 17] Available at: https://urn.nsk.hr/urn:nbn:hr:159:156273

K. Paradžik, "Primjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:159:156273

Metadata
TitlePrimjena spektroskopije nuklearne magnetske rezonancije u metabolomičkim istraživanjima
Title (english)Application of nuclear magnetic resonance spectroscopy in metabolomic research
AuthorKatarina Paradžik
MentorLidija Barišić (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Organic Chemistry)
Zagreb
Defense date and country2023-09-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Spektroskopija nuklearne magnetske rezonancije (NMR), metoda koja se zasniva na magnetskim svoj-stvima jezgara s neparnim atomskim brojem, ima sve veću primjenu u analizi sastava bioloških uzoraka poput urina i krvi. Metabolomika se bavi biokemijskom karakterizacijom metaboloma i njegovih prom-jena uzrokovanih upotrebom lijekova te genetičkim, nutritivnim i okolišnim faktorima. Promjene u sa-stavu metabolita indikator su općeg stanja organizma te je identifikacija i kvantifikacija metabolita klju-čna za predviđanje bolesti, praćenje učinkovitosti terapije te istraživanje utjecaja okolišnih uvjeta na organizam. Visoka reproducibilnost, mogućnost kvantitativne analize te neinvazivnost čine NMR po-godnom metodom za određivanje sastava metaboloma.
Abstract (english)
Nuclear Magnetic Resonance (NMR) spectroscopy, a method based on the magnetic properties of odd-atomic-number nuclei, is increasingly being used to analyse the composition of biological samples such as urine and blood. Metabolomics involves the biochemical characterization of the metabolome and its changes caused by drug usage, genetic, nutritional, and environmental factors. Changes in metabolite composition are indicative of the overall health of an organism, and identification and quantification of metabolites is critical for predicting disease, monitoring the effectiveness of therapy, and studying the effects of environmental conditions on the body. High reproducibility, the ability to perform quantitative analysis and a non-invasive approach make NMR a suitable method for determining the composition of the metabolome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:156273
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2023-09-22 08:29:11