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undergraduate thesis
Terapijski enzimi mikrobnog podrijetla
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2022. urn:nbn:hr:159:245310
Miše, Toni Slavko
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Antibiotic, Enzyme, Probiotic and Starter Cultures Technology

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Miše, T. S. (2022). Terapijski enzimi mikrobnog podrijetla (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:245310

Miše, Toni Slavko. "Terapijski enzimi mikrobnog podrijetla." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2022. https://urn.nsk.hr/urn:nbn:hr:159:245310

Miše, Toni Slavko. "Terapijski enzimi mikrobnog podrijetla." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2022. https://urn.nsk.hr/urn:nbn:hr:159:245310

Miše, T. S. (2022). 'Terapijski enzimi mikrobnog podrijetla', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 27 December 2024, https://urn.nsk.hr/urn:nbn:hr:159:245310

Miše TS. Terapijski enzimi mikrobnog podrijetla [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2022 [cited 2024 December 27] Available at: https://urn.nsk.hr/urn:nbn:hr:159:245310

T. S. Miše, "Terapijski enzimi mikrobnog podrijetla", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:159:245310

Metadata
TitleTerapijski enzimi mikrobnog podrijetla
Title (english)Therapeutic enzymes of microbial origin
AuthorToni Slavko Miše
MentorBlaženka Kos (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Antibiotic, Enzyme, Probiotic and Starter Cultures Technology)
Zagreb
Defense date and country2022-07-07, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Biofarmaceutika je brzo rastuće područje unutar kojeg se provode istraživanja i koriste stanične linije, mikroorganizmi i njihovi proizvodi za terapijsku primjenu. Enzimi su izvanredni biokatalizatori koji ubrzavaju biokemijske reakcije. Posjeduju nekoliko specifičnih značajki kao što su velik katalitički potencijal, velika specifičnost za supstrat, kao i pH i temperaturni optimumi njihove katalitičke aktivnosti. Zbog ovih izvanrednih svojstava pronalaze različite kliničke primjene i sve se više koriste za liječenje širokog spektra bolesti, samostalno ili u kombinaciji s drugim terapijama, te čine važnu podskupinu modernih biofarmaceutika. Terapijska primjena enzima uključuje protuupalne agense, enzibiotike, fibrinolitičke agense, agense protiv tumora, probavne terapijske enzime, kao i enzime za rijetke bolesti. Razvoj novih terapijskih enzima kao i nadogradnja i poboljšanja postojećih primjenom proteinskog inženjerstva su prioritet. Izolaciju, regulaciju, proizvodnju i primjenu enzima kao biofarmaceutika treba unaprijediti do maksimalnog potencijala kako bi se iskoristile njihove prednosti u odnosu na kemijska terapijska sredstva u liječenju različitih bolesti.
Abstract (english)
Biopharmaceuticals is a fast emerging field that explores and employs biological organisms and their products for therapeutic applications. Enzymes are biocatalysts that accelerate the rate of biochemical reactions. They possess features like catalytic potential, substrate specificity as well as pH and temperature optima. Due to these attributes, they find diverse clinical applications, and are increasingly used to treat a wide range of diseases, alone or in combination with other therapies, so they are importan subclass of biopharmaceutics. Therapeutic applications of enzymes include anti‐ inflammatory agents, enzybiotics, fibrinolytic agents, anticancer agents, digestive therapeutic enzymes, as well as enzymes for rare diseases. Developement of new therapeutic enzymes as well as upgrading and improving existing ones using protein engineering are a priority. The isolation, regulation, production and application of microbial enzymes as biopharmaceuticals should be improved to the maximum potential in order to utilize their advantages over chemical therapeutic agents in the treatment of various diseases.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:245310
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2024-04-10 12:21:42