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master's thesis
Računalna analiza modela metabolizma glavnih nutrijenata
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. urn:nbn:hr:159:259755
Nadoveza, Sara
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Process Engineering
Laboratory for Measurement, Regulation and Automatisation

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Nadoveza, S. (2023). Računalna analiza modela metabolizma glavnih nutrijenata (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:259755

Nadoveza, Sara. "Računalna analiza modela metabolizma glavnih nutrijenata." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. https://urn.nsk.hr/urn:nbn:hr:159:259755

Nadoveza, Sara. "Računalna analiza modela metabolizma glavnih nutrijenata." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2023. https://urn.nsk.hr/urn:nbn:hr:159:259755

Nadoveza, S. (2023). 'Računalna analiza modela metabolizma glavnih nutrijenata', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 29 July 2024, https://urn.nsk.hr/urn:nbn:hr:159:259755

Nadoveza S. Računalna analiza modela metabolizma glavnih nutrijenata [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2023 [cited 2024 July 29] Available at: https://urn.nsk.hr/urn:nbn:hr:159:259755

S. Nadoveza, "Računalna analiza modela metabolizma glavnih nutrijenata", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:159:259755

Metadata
TitleRačunalna analiza modela metabolizma glavnih nutrijenata
Title (english)Computer analysis of main nutrient metabolism models
AuthorSara Nadoveza
MentorAna Jurinjak Tušek (mentor)
Committee memberJasenka Gajdoš Kljusurić (predsjednik povjerenstva)
Committee memberMaja Benković (član povjerenstva)
Committee memberIvana Rumora Samarin (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Process Engineering)
(Laboratory for Measurement, Regulation and Automatisation)
Zagreb
Defense date and country2023-05-31, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Abstract
U ovom radu provedena je simulacija modela metabolizma glavnih nutrijenata pomoću softverskog alata CellDesigner. Napravljena su četiri jelovnika za četiri dana, namijenjena za dijabetičare, iz kojih su izračunate početne koncentracije ugljikohidrata, masti i proteina. Na temelju početnih koncentracija glavnih nutrijenata uspješno je provedena simulacija modela metabolizma. Rezultati ukazuju na sličan odgovor nutrijenata za sva četiri dana jer se radi o reguliranim jelovnicima čija je primarna uloga regulacija glukoze u krvi. Također je provedena analiza lokalne osjetljivosti parametara gdje je glavni cilj uočiti kako promjene u vrijednosti parametara utječu na izlazne varijable modela. Rezultati su pokazali kako promjena vrijednosti parametara k5, K5, k9 te K9 ima najveći utjecaj na acetil-CoA.
Abstract (english)
In this work, a simulation of the metabolism model of the main nutrients was carried out using the CellDesigner software tool. Four menus for four days were created, intended for diabetics, from which the initial concentrations of carbohydrates, fats and proteins were calculated. Based on the initial concentrations of the main nutrients, the simulation of the metabolism model was successfully carried out. The results indicate a similar response of nutrients for all four days, as these are regulated menus whose primary role is blood glucose regulation. An analysis of the local sensitivity of the parameters was also performed, where the main goal is to observe how changes in the parameter values affect the output variables of the model. The results showed that the change in the value of parameters k5, K5, k9 and K9 has the greatest impact on acetyl-CoA.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:259755
Study programmeTitle: Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra nutricionizma (magistar/magistra nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) icon
Created on2024-05-15 10:55:20