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master's thesis
Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2024. urn:nbn:hr:159:699723
Galić, Mia
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Biology and Microbial Genetics

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

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Galić, M. (2024). Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:699723

Galić, Mia. "Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2024. https://urn.nsk.hr/urn:nbn:hr:159:699723

Galić, Mia. "Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2024. https://urn.nsk.hr/urn:nbn:hr:159:699723

Galić, M. (2024). 'Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:699723

Galić M. Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2024 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:159:699723

M. Galić, "Istraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:159:699723

Metadata
TitleIstraživanje utjecaja odabranih aktivnih tvari iz pesticida na ekspresiju gena primjenom in silico analiza
Title (english)Research on the impact of selected active substances from pesticides on gene expression using in silico analysis
AuthorMia Galić
MentorKsenija Durgo (mentor)
MentorAna Huđek Turković (pomoć pri izradi, neposredni voditelj)
Committee memberMarina Krpan (predsjednik povjerenstva)
Committee memberAna Butorac (član povjerenstva)
Committee memberTeuta Murati (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Biology and Microbial Genetics)
Zagreb
Defense date and country2024-06-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
U ovom radu istraživan je utjecaj pesticida na ekspresiju gena pomoći in silico analize. Pesticidi čiji je utjecaj istraživan su: glifosat, kaptan, spinosad, deltametrin, acetamiprid, nikosulfuron, S-metolaklor i terbutilazin. Upotreba in silico metoda sve je više uznapredovala te se koriste radi relativno brzog prikupljanja podataka o toksičnosti tvari koje nije moguće potpuno ispitati standardnim toksikološkim testovima ili pak za tvari za koje postoje podaci dobiveni standardnim metodama kako bi se provjerila valjanost modela. In silico metode se mogu primijeniti s ciljem relativno brzog dobivanja podataka o toksičnosti supstanci koje nije moguće u potpunosti ispitati standardnim toksikološkim testovima. U radu su korištene dvije online baze podataka: „Comparative toxicogenomics database“ (CTD) i „String“. One sadrže podatke o toksičnom djelovanju pesticida. U ovom radu, usmjerenost je bila na utjacaju pesticida na ekspresiju gena u ljudskom genomu.
Abstract (english)
This study investigates the impact of pesticides on gene expression using in silico analysis. The pesticides investigated include glyphosate, captan, spinosad, deltamethrin, acetamiprid, nicosulfuron, S-metolachlor, and terbuthylazine. The use of in silico methods has advanced significantly, providing quick data collection on the toxicity of substances that cannot be fully examined by standard toxicological tests, or for substances with existing data obtained by standard methods to verify model validity. In silico methods can be applied to obtain relatively fast data on the toxicity of substances that cannot be fully examined by standard toxicological tests. The study utilized two online databases: the Comparative Toxicogenomics Database (CTD) and String, both containing data on the toxic effects of pesticides. The focus of this study was on the impact of pesticides on gene expression in the human genome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:699723
Study programmeTitle: Food Safety Management
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane (magistar/magistra inženjer/inženjerka upravljanja sigurnošću hrane)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) icon
Created on2024-10-30 13:17:59