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undergraduate thesis
Sigurnost upotrebe aspartama u prehrani
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2013. urn:nbn:hr:159:736740
Čagalj, Mia
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Chemistry and Biochemistry
Laboratory for Toxicology

Institutional repository: Repository of the Faculty of Food Technology and Biotechnology

Cite this document

Čagalj, M. (2013). Sigurnost upotrebe aspartama u prehrani (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:736740

Čagalj, Mia. "Sigurnost upotrebe aspartama u prehrani." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2013. https://urn.nsk.hr/urn:nbn:hr:159:736740

Čagalj, Mia. "Sigurnost upotrebe aspartama u prehrani." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2013. https://urn.nsk.hr/urn:nbn:hr:159:736740

Čagalj, M. (2013). 'Sigurnost upotrebe aspartama u prehrani', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 16 January 2025, https://urn.nsk.hr/urn:nbn:hr:159:736740

Čagalj M. Sigurnost upotrebe aspartama u prehrani [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2013 [cited 2025 January 16] Available at: https://urn.nsk.hr/urn:nbn:hr:159:736740

M. Čagalj, "Sigurnost upotrebe aspartama u prehrani", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2013. Available at: https://urn.nsk.hr/urn:nbn:hr:159:736740

Metadata
TitleSigurnost upotrebe aspartama u prehrani
Title (english)The safety of aspartame use in diet
AuthorMia Čagalj
MentorBranimir Šimić (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Chemistry and Biochemistry)
(Laboratory for Toxicology)
Zagreb
Defense date and country2013-09-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Abstract
Aspartam je umjetno sladilo koje se koristi umjesto saharoze. Njegova kalorijska vrijednost iznosi 4 kcal/g, no u upotrebi može se primjenjivati u 200 puta manjoj količini u odnosu na šećer zahvaljujući njegovoj intenzivnoj slatkoći. Strukturno je sastavljen je od L-fenilalanin metil estera i L-asparaginske kiseline. Metabolizira se u gastrointestinalnom traktu na 3 komponente – aspartat, fenilalanin i metanol. Zbog moguće toksičnosti ovih metabolita, postoje pretpostavke o potencijalnoj štetnosti aspartama. Provedena su mnoga istraživanja na ljudskim i životinjskim modelima, a u ovom radu dan je pregled dosadašnjih saznanja o biotransformacijama i toksičnosti aspartama. Na temelju rezultata o povezanosti upotrebe aspartama s alergijama, glavoboljama, epileptičnim napadajima, fenilketonurijom, učincima na endokrini sustav i kancerogenezu, zaključuje se da ne postoje čvrsti dokazi o štetnosti aspartama za ljudsko zdravlje.
Abstract (english)
Aspartame is an artificial sweetener used instead of saccharose. Its caloric value is 4 kcal/g, but it can be added in an amount which is 200 times less than the amount of sugar, thanks to its intensive sweetness. Aspartame is composed of L-phenylalanine methyl ester and L- aspartic acid. It is metabolized in the gastrointestinal tract in 3 components – aspartic acid, phenylalanine and methanol. Because of the possible toxicity of this 3 components there are many assumptions about the potential harmfulness of aspartame. Many studies have been conducted on human and animal models, and this is a review on the previous knowledge about biotransformations and aspartame toxicity. Based on the results of the correlation of aspartame with allergies, epileptic seizures, phenylketonuria, effects on the endocrine system and with cancerogenesis, it can be concluded that there are no firm evidence about the harmfulness of aspartame on the human health.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:736740
Study programmeTitle: Nutrition
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2017-05-04 09:23:28