Grapevine yellows a quarantine disease of grape vine caused by phytoplasm. It is considered one of the most dangerous diseases of grape vines in Europe, which came from America in the mid-20th century. It is widespread with the American cricket, if it does not take appropriate measures to treat and control the disease quickly, it takes on the scale of the epidemic. The disease of grapevine yellow in Croatia appeared in 2009 in Karlovac County, and in the last decade it spread to a wider wine-growing area. The greatest danger is in the Istrian County. To control this highly contagious disease, it is important to detect any symptoms and occur as early as possible. During the discovery period - which coincides with the vintage and is very short, it is difficult to manually check the entire vineyard and determine the symptoms of the disease. Therefore, we have been guided by experience and research in France and acquainted with the many possibilities offered by drones to opt for remote detection of grapevine yellows . The benefits of recording are numerous; in a very short time to reach the actual condition of the area, quickly and easily infected vines recognized in the whole vineyard. The drone Sensefly eBee Plus flies independently with the help of an integrated GPS receiver and navigation system and a flying flight autopilot. The Emotion3, Pix4D and Globall Mapper software greatly facilitates the creation of missions, task execution, data processing and detecting the desired disease. The vineyard selected for the recording was in Istria, Municipality of Vizinada by the wine-maker EliĎa Pilata. Family vineyard is about 18 hectares, and in the last couple of years an ever greater problem is its FD because of its dramatically reduced yield of grapes. The greatest danger comes from the surrounding neglected and unprocessed vineyards in which the disease prevails. A wider area around the vineyards was recorded - 67 ha and it was found: 10 completely abandoned vineyards and 58 different locations with individual infected plants. A total of 103 infected cans were found with SEQUIO's multi-spectrum camera in the entire vineyard area of about 2 ha. Infected plantes are mostly at the edges, opposite to which there is an abandoned and grazed vineyard. Total recording cost: S.O.D.A. camera – wider area of vineyard, multi-spectrum SEQUIO camera - vineyard, data processing, travel cost and other costs 11 112 kn. If properly used the recorded data and kept the precautionary measure in accordance with the law, the money spent would be returned to hard working wine growers living in this branch of agriculture in Istria.