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master's thesis
Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. urn:nbn:hr:163:545629
Tipurić, Tea
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical analysis

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Tipurić, T. (2018). Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:545629

Tipurić, Tea. "Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:545629

Tipurić, Tea. "Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:545629

Tipurić, T. (2018). 'Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 09 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:545629

Tipurić T. Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2018 [cited 2024 November 09] Available at: https://urn.nsk.hr/urn:nbn:hr:163:545629

T. Tipurić, "Mogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:163:545629

Metadata
TitleMogućnosti primjene HSS-GC-FID tehnike za analizu lakohlapljivih polarnih sastavnica u vlažnim maramicama
Title (english)Possible application of the HSS-GC-FID technique for the analysis of polar volatile compounds in wet wipes
AuthorTea Tipurić
MentorMiranda Sertić (mentor)
Committee memberMiranda Sertić (predsjednik povjerenstva)
Committee memberBiljana Nigović (član povjerenstva)
Committee memberIvana Perković (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical analysis)
Zagreb
Defense date and country2018-05-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Brojni kozmetički oblici danas su dostupni u obliku vlažnih maramica pakiranih u plastične omote. Vlažne maramice za jednokratnu uporabu koriste se za njegu dječje kože, pranje ruku, intimnu higijenu, uklanjanje šminke, čišćenje u kućanstvu i dr., a većina se ubraja u kozmetičke proizvode. Samim time, zakonom su regulirane samo neke od sastavnica, dok za ostale većinom nema informacija o količini i potencijalnoj štetnosti na zdravlje. U ovom radu istražuje se mogućnost primjene metode headspace plinske kromatografije s plamenoionizacijskim detektorom za identifikaciju i kvantitativno određivanje pet odabranih lakohlapljivih sastavnica u maramicama: metanol, etanol, aceton, izopropanol i etil-acetat. Njihova prisutnost u maramicama je dokazana usporedbom vremena zadržavanja analita u uzorku i u standardnoj otopini. Zbog slabe ponovljivosti rezultata mjerenja metoda se nije pokazala pouzdanom za određivanje sadržaja, i daljnja istraživanja treba usmjeriti ka otkrivanju potencijalnih grešaka u analizi, dodatnoj optimizaciji uvjeta ili razvoju sasvim nove metode. Mjerenja provedena u sklopu ovoga rada otvaraju raspravu o problematici analize sastava čvrstog uzorka bez prethodne ekstrakcije analita i nameću razmatranje uvođenja dodatnih koraka u analizu, što bi mogao biti predmet nekih budućih istraživanja. Kao jedan od navedenih dodatnih koraka posebno se ističe moguća priprema uzorka metodom mikroekstrakcije na čvrstoj fazi (SPME), što svakako ostavlja prostora za istraživanja koja slijede.
Abstract (english)
Numerous cosmetic products are available today in the form of wet wipes packed in plastic wraps. Single-use wet wipes are used for baby skin care, hand washing, intimate hygiene, makeup remover, household cleaning, and most of which are listed as cosmetic products. Consequently, only some of the constituents are regulated by law, while for the rest, there is no information on quantity and potential health hazard. This paper investigats the possibility of using a previously developed HSS-GC-FID method to determine the presence and content of five selected analytes in wipes: methanol, ethanol, acetone, isopropanol and ethyl acetate. Their presence in wipes was demonstrated by comparing retention times of analytes in the sample and in the standard solution. Due to the poor reproducibility of measurement results, the method did not show any reliability for the determination of content, and further research should focus on detecting potential errors in analysis, additional optimization of conditions, or development of a completely new method. Measurements carried out within this paper open the discussion on the problem of solid sample composition analysis without previous analytical extraction and require consideration of the introduction of additional steps in the analysis, which could be the subject of some future research. As one of the above mentioned steps, the possible preparation of the sample by the solid phase microextraction method (SPME) is particularly emphasized, which leaves space for further research.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:545629
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-01-16 14:17:22