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professional thesis
Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. urn:nbn:hr:163:706365
Zekić, Josip
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Zekić, J. (2018). Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc. (Professional thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:706365

Zekić, Josip. "Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:706365

Zekić, Josip. "Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:706365

Zekić, J. (2018). 'Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.', Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:706365

Zekić J. Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc. [Professional thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2018 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:163:706365

J. Zekić, "Fitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.", Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:163:706365

Metadata
TitleFitokemijski sastav i biološki učinci gljive Cordyceps sinensis (Berk.) Sacc.
AuthorJosip Zekić
MentorSanda Vladimir-Knežević (mentor)
Committee memberMarijana Zovko Končić (predsjednik povjerenstva)
Committee memberSanda Vladimir-Knežević (član povjerenstva)
Committee memberAntun Alegro (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Zagreb
Defense date and country2018-05-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Cilj istraživanja Cilj ovog specijalističkog rada je pregled podataka o bioaktivnim sastavnicama i farmakološkim učincima kineskog kordicepsa da se ustanovi postoje li znanstveni temelji za tradicionalnu uporabu ove gljive te koja pitanja ostaju otvorena za daljnja istraživanja. Materijal i metode Istraživanje u okviru ovog rada je teorijskog karaktera i uključuju pregled dostupne znanstvene i stručne literature o predloženoj temi. U pretraživanju su korištene relevantne elektronske mrežne stranice te bibliografske baze podataka kao što su: Current Contents, ScienceDirect, Scopus, PubMed, Medline i Cocharen Library. Rezultati Cordyceps sinensis (Berk.) Sacc. je ljekovita gljiva koja već stoljećima zauzima značajno mjesto u tradicionalnoj kineskoj medicini. Entomopatogena je gljiva rasprostranjena na Tibetanskoj visoravni i Himalajima. Nukleozidi, polisaharidi i steroli identificirani su kao glavne bioaktivne sastavnice. Brojne pretkliničke i nekoliko kliničkih studija pokazale su da ekstrakti kineskog kordicepsa te izolirani polisaharidi i kordicepin posjeduju antioksidativnu, protuupalnu, imunomodulacijsku i antitumorsku aktivnost, reguliraju glikemiju i metabolizam lipida te jačaju fizičku izdržljivost i smanjuju osjećaj umora. Zaključci Mnogi znanstveni dokazi upućuju na blagotvorne učinke kineskog kordicepsa na ljudsko zdravlje, Međutim, potrebne su buduće kliničke studije kojima će se ustanoviti njegova terapijska učinkovitost i sigurnost primjene.
Abstract (english)
Objectives The purpose of this specialist work is to review the data on bioactive constituents and the pharmacological effects of Chinese cordyceps to determine if there are scientific bases for the traditional use of this fungus and what issues remain open for further research. Material and methods Research in this paper is a theoretical one and includes a detailed overview of the available professional and scientific data on the topic. Relevant websites and bibliographic database such as Current Contents, ScienceDirect, Scopus, PubMed, Medline and Lexicomp are searched. Results Cordyceps sinensis (Berk.) Sacc. is a medicinal mushroom which has been a highly regarded cornerstone of Chinese medicine for centuries. It is an entamophagus fungus, naturally distributed in the Tibetan Plateau and Himalayas. Nucleosides, polysaccharides and sterols detected as the major bioactive constituents. Numerous preclinical and several clinical studies have shown that cordyceps extracts, isolated polysaccharides and cordycepin possess antioxidative, anti-inflammatory, immunomodulatory and antitumor activity, regulate glycemia and lipid metabolism, and enhance physical endurance and reduce fatigue. Conclusion Much scientific evidence shows the beneficial effects of Chinese cordyceps on human health. However, further clinical trials are required to establish therapeutic its efficacy and safety in humans.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:706365
Study programmeTitle: Phytopharmacy with dietotherapy
Study programme type: university
Study level: postgraduate specialist
Academic / professional title: sveučilišni magistar/sveučilišna magistra fitofarmacije s dijetoterapijom (sveučilišni magistar/sveučilišna magistra fitofarmacije s dijetoterapijom)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-03-06 14:47:43