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master's thesis
Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. urn:nbn:hr:163:322394
Perčić, Eva
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Perčić, E. (2019). Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:322394

Perčić, Eva. "Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:322394

Perčić, Eva. "Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:322394

Perčić, E. (2019). 'Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:322394

Perčić E. Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2019 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:163:322394

E. Perčić, "Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:163:322394

Metadata
TitleFarmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi
Title (english)Pharmacotherapeutic specificities of the most common anesthetic in the elderly
AuthorEva Perčić
MentorPetra Turčić (mentor)
Committee memberPetra Turčić (predsjednik povjerenstva)
Committee memberAna-Marija Domijan (član povjerenstva)
Committee memberJasminka Peršec (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacology)
Zagreb
Defense date and country2019-06-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Anestezija je postupak kojim se pacijent dovodi u stanje neosjetljivosti. Razlikujemo opću i lokalnu, odnosno regionalnu anesteziju. Opći anestetici mogu se podijeliti na inhalacijske i intravenske, a osim njih u anesteziji se koriste opioidni analgetici i neuromuskularni blokatori. Kad god je moguće, preferira se regionalna anestezija, osobito kod starije populacije. Starijom populacijom smatraju se svi ljudi stariji od 65 godina. Starenje je progresivni proces karakteriziran promjenama u strukturi i funkciji organa i tkiva. Najznačajnije promjene događaju se u kardiovaskularnom, respiratornom, živčanom i hepatorenalnom sustavu. Također se smanjuje sposobnost regulacije tjelesne temperature što predstavlja problem tijekom kirurških zahvata. Farmakodinamske i farmakokinetske karakteristike lijekova mogu se mijenjati, što dovodi do veće osjetljivosti gerijatrijskih pacijenata na anestetike, čime se povećava rizik za pojavu neželjenih učinaka. Za postizanje istog kliničkog efekta kao kod mlađih osoba, potrebna je redukcija doze općih i lokalnih anestetika, opioidnih analgetika, sedativa i neuromuskularnih blokatora.
Abstract (english)
Anaesthesia is a procedure which leads the patient to a state of insensitivity. It is divided to general and local or regional anesthesia. General anesthetics can be divided into inhaled and intravenous, besides them opioid analgesics and neuromuscular blockers are also used in anesthesia. Whenever possible, regional anesthesia is preferred, especially in the elderly. The older population is considered to be all people over the age of 65. Aging is a progressive process characterized by changes in the structure and function of organs and tissues. The most significant changes occur in the cardiovascular, respiratory, nervous and hepatorenal system. Also the ability to regulate body temperature is reduced, what is the problem during surgical procedures. Pharmacodynamic and pharmacokinetic properties of drugs may change, resulting in greater sensitivity of geriatric patients to anesthetics, thereby increasing the risk of adverse effects. To achieve the same clinical effect as in younger subjects, dose reduction of general and local anesthetics, opioid analgetics, sedatives and neuromuscular blocking agents is required.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:322394
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-02-12 13:11:49