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master's thesis
Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. urn:nbn:hr:163:979918
Pešić, Marija
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Pešić, M. (2019). Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:979918

Pešić, Marija. "Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:979918

Pešić, Marija. "Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:979918

Pešić, M. (2019). 'Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:979918

Pešić M. Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2019 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:163:979918

M. Pešić, "Razlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:163:979918

Metadata
TitleRazlike između hemangioma i vaskularnih malformacija i farmakoterapija u djece
Title (english)Differences between hemangioma and vascular malformation and pharmacotherapy in children
AuthorMarija Pešić
MentorPetra Turčić (mentor)
MentorArnes Rešić (mentor)
Committee memberPetra Turčić (predsjednik povjerenstva)
Committee memberMarija Grdić Rajković (član povjerenstva)
Committee memberArnes Rešić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacology)
Zagreb
Defense date and country2019-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Dojenački hemangiom je benigni vaskularni tumor sa visokom incidencijom u djece, karakterizira ga abnormalna proliferacija endotelnih stanica kao i abnormalna arhitektura krvnih žila. Vaskularne malformacije su urođene pogreške vaskularne morfogeneze, prisutne su odmah nakon rođenja. Kako bi se spriječile pogreške u dijagnozi i liječenju, potrebno je detaljno razlikovati ove dvije skupine vaskularnih anomalija. U liječenju infantilnog hemangioma, najučinkovitiji je oralno primijenjen propranolol, dok se liječenje vaskularnih malformacija provodi laserski, skleroterapijom, kirurškim procesima, embolizacijom i rjeđe farmakoterapijom. Zbog česte pojavnosti na području lica i vrata, ove anomalije uvelike definiraju fizički izgled pacijenta pa mogu utjecati na njegov psihološki profil i samopouzdanje. Kako bi se optimizirala terapija, nužna su dodatna znanstvena istraživanja mehanizama nastajanja ovih bolesti kao i detaljnih mehanizma djelovanja primijenjenih lijekova.
Abstract (english)
Infantile hemangioma is benign vascular tumor with high incidence and is characterized by abnormal endothelial cell proliferation as well as abnormal blood vessel architecture. Vascular malformations are congenital errors of vascular morphogenesis, present immediately after birth. To prevent errors in diagnosis and treatment, these two groups of vascular anomalies need to be precisely differentiated. In the treatment of infantile hemangioma, the most effective therapy is orally administered propranolol, while the treatment of vascular malformations is performed by laser, sclerotherapy, surgical processes, embolization and rarely pharmacotherapy. Because of their frequent appearance in the face and neck area, these anomalies greatly define physical appearance of the patient and can affect his psychological profile and self-confidence. In order to achieve optimal therapy additional scientific research is needed to clarify the mechanisms of these diseases as well as the detailed mechanisms of action of the drugs administered.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:979918
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-03-05 13:23:50