prikaz prve stranice dokumenta Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs
  Download
PDF 496.96 KB
Scientific paper - Original scientific paper
Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs
Acta Pharmaceutica, 69 (2019), 4; 461-482. https://doi.org/10.2478/acph-2019-0052
TORIĆ, JELENA; KARKOVIĆ MARKOVIĆ, ANA; JAKOBUŠIĆ BRALA, CVIJETA; BARBARIĆ, MONIKA

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

TORIĆ, J., KARKOVIĆ MARKOVIĆ, A., JAKOBUŠIĆ BRALA, C. & BARBARIĆ, M. (2019). Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs. Acta Pharmaceutica, 69. (4), 461-482. doi: 10.2478/acph-2019-0052

TORIĆ, JELENA, et al. "Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs." Acta Pharmaceutica, vol. 69, no. 4, 2019, pp. 461-482. https://doi.org/10.2478/acph-2019-0052

TORIĆ, JELENA, ANA KARKOVIĆ MARKOVIĆ, CVIJETA JAKOBUŠIĆ BRALA and MONIKA BARBARIĆ. "Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs." Acta Pharmaceutica 69, no. 4 (2019): 461-482. https://doi.org/10.2478/acph-2019-0052

TORIĆ, J., et al. (2019) 'Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs', Acta Pharmaceutica, 69(4), pp. 461-482. doi: 10.2478/acph-2019-0052

TORIĆ J, KARKOVIĆ MARKOVIĆ A, JAKOBUŠIĆ BRALA C, BARBARIĆ M. Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs. Acta Pharmaceutica [Internet]. 2019 [cited 2024 August 27];69(4):461-482. doi: 10.2478/acph-2019-0052

J. TORIĆ, A. KARKOVIĆ MARKOVIĆ, C. JAKOBUŠIĆ BRALA and M. BARBARIĆ, "Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs", Acta Pharmaceutica, vol. 69, no. 4, pp. 461-482, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:624933. [Accessed: 27 August 2024]

Metadata
Title (english)Anticancer effects of olive oil polyphenols and their combinations with anticancer drugs
AuthorJELENA TORIĆ
AuthorANA KARKOVIĆ MARKOVIĆ
AuthorCVIJETA JAKOBUŠIĆ BRALA
AuthorMONIKA BARBARIĆ
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of physical chemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Cancer presents one of the leading causes of death in the world. Current treatment includes the administration of one or more anticancer drugs, commonly known as chemotherapy. The biggest issue concerning the chemotherapeutics is their toxicity on normal cells and persisting side effects. One approach to the issue is chemoprevention and the other one is the discovery of more effective drugs or drug combinations, including combinations with polyphenols. Olive oil polyphenols (OOPs), especially hydroxytyrosol (HTyr), tyrosol (Tyr) and their derivatives oleuropein (Ole), oleacein and oleocanthal (Oc) express anticancer activity on different cancer models. Recent studies report that phenolic extract of virgin olive oil may be more effective than the individual phenolic compounds. Also, there is a growing body of evidence about the combined treatment of OOPs with various anticancer drugs, such as cisplatin, tamoxifen, doxorubicin and others. These novel approaches may present an advanced strategy in the prevention and treatment of cancer.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Pharmaceutica
Numberingvol. 69, no. 4, pp. 461-482
p-ISSN1330-0075
e-ISSN1846-9558
DOIhttps://doi.org/10.2478/acph-2019-0052
URN:NBNurn:nbn:hr:163:624933
Publication2019
Document URLhttps://hrcak.srce.hr/225431
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-06 16:04:40