prikaz prve stranice dokumenta Phenolic compounds of Iris adriatica and their antimycobacterial effects
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Scientific paper - Original scientific paper
Phenolic compounds of Iris adriatica and their antimycobacterial effects
Acta Pharmaceutica, 69 (2019), 4; 673-681. https://doi.org/10.2478/acph-2020-0037
Ochensberger, Sandra; Alperth, Fabian; Mitić, Božena; Kunert, Olaf; Mayer, Stefanie; Ferreira Mourao, Maria; Turek, Ivana; Vlad Luca, Simon; Skalicka-Wozniak, Krystina; Maleš, Željan; Hruševar, Dario; Duka, Ivan; Bucar, Franz

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Ochensberger, S., Alperth, F., Mitić, B., Kunert, O., Mayer, S., Ferreira Mourao, M. ... Bucar, F. (2019). Phenolic compounds of Iris adriatica and their antimycobacterial effects. Acta Pharmaceutica, 69. (4), 673-681. doi: 10.2478/acph-2020-0037

Ochensberger, Sandra, et al. "Phenolic compounds of Iris adriatica and their antimycobacterial effects." Acta Pharmaceutica, vol. 69, no. 4, 2019, pp. 673-681. https://doi.org/10.2478/acph-2020-0037

Ochensberger, Sandra, Fabian Alperth, Božena Mitić, Olaf Kunert, Stefanie Mayer, Maria Ferreira Mourao, Ivana Turek, et al. "Phenolic compounds of Iris adriatica and their antimycobacterial effects." Acta Pharmaceutica 69, no. 4 (2019): 673-681. https://doi.org/10.2478/acph-2020-0037

Ochensberger, S., et al. (2019) 'Phenolic compounds of Iris adriatica and their antimycobacterial effects', Acta Pharmaceutica, 69(4), pp. 673-681. doi: 10.2478/acph-2020-0037

Ochensberger S, Alperth F, Mitić B, Kunert O, Mayer S, Ferreira Mourao M, and sur.. Phenolic compounds of Iris adriatica and their antimycobacterial effects. Acta Pharmaceutica [Internet]. 2019 [cited 2024 December 28];69(4):673-681. doi: 10.2478/acph-2020-0037

S. Ochensberger, et al., "Phenolic compounds of Iris adriatica and their antimycobacterial effects", Acta Pharmaceutica, vol. 69, no. 4, pp. 673-681, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:847372. [Accessed: 28 December 2024]

Metadata
Title (english)Phenolic compounds of Iris adriatica and their antimycobacterial effects
AuthorSandra Ochensberger
AuthorFabian Alperth
AuthorBožena Mitić
AuthorOlaf Kunert
AuthorStefanie Mayer
AuthorMaria Ferreira Mourao
AuthorIvana Turek
AuthorSimon Vlad Luca
AuthorKrystina Skalicka-Wozniak
AuthorŽeljan Maleš
AuthorDario Hruševar
AuthorIvan Duka
AuthorFranz Bucar
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical botany)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Little is known about the pharmacological activities of Iris adriatica (Iridaceae), a plant en-demic to Dalmatia (Croatia). For this purpose, we performed a bioassay-guided fractionation including high-performance counter current chromatography (HPCCC) and antibacterial tests using Mycobacterium smegmatis mc² 155. One obtained fraction was found to be antimyco-bacterially active with a MIC of 64 mg L-1. Furthermore, fractions were tested for resistance modulatory effects using ethidium bromide as substrate. We were able to identify the pure isoflavonic compounds irigenin and irilone and a fraction containing mainly the benzophenone 2,4,6-trihydroxy-4-methoxy-benzophenone to be responsible for the resistance-modulatory activity of this plant.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Pharmaceutica
Numberingvol. 69, no. 4, pp. 673-681
p-ISSN1330-0075
e-ISSN1846-9558
DOIhttps://doi.org/10.2478/acph-2020-0037
URN:NBNurn:nbn:hr:163:847372
Publication2019
Document URLhttps://hrcak.srce.hr/220899
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-07 15:29:10