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Scientific paper - Preliminary note / Short communication
Zašto treba prepoznati makroenzime?
Biochemia Medica, 17 (2007), 1; 52-59. urn:nbn:hr:163:017429
Čepelak, Ivana; Čvorišćec, Dubravka

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Čepelak, I. & Čvorišćec, D. (2007). Zašto treba prepoznati makroenzime?. Biochemia Medica, 17. (1), 52-59. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:017429

Čepelak, Ivana and Dubravka Čvorišćec. "Zašto treba prepoznati makroenzime?." Biochemia Medica, vol. 17, no. 1, 2007, pp. 52-59. https://urn.nsk.hr/urn:nbn:hr:163:017429

Čepelak, Ivana and Dubravka Čvorišćec. "Zašto treba prepoznati makroenzime?." Biochemia Medica 17, no. 1 (2007): 52-59. https://urn.nsk.hr/urn:nbn:hr:163:017429

Čepelak, I. and Čvorišćec, D. (2007) 'Zašto treba prepoznati makroenzime?', Biochemia Medica, 17(1), pp. 52-59. Available at: https://urn.nsk.hr/urn:nbn:hr:163:017429 (Accessed 09 November 2024)

Čepelak I, Čvorišćec D. Zašto treba prepoznati makroenzime?. Biochemia Medica [Internet]. 2007 [cited 2024 November 09];17(1):52-59. Available at: https://urn.nsk.hr/urn:nbn:hr:163:017429

I. Čepelak and D. Čvorišćec, "Zašto treba prepoznati makroenzime?", Biochemia Medica, vol. 17, no. 1, pp. 52-59, 2007. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:017429. [Accessed: 09 November 2024]

Metadata
Title (croatian)Zašto treba prepoznati makroenzime?
Title (english)Why is it necessary to recognize macroenzymes?
AuthorIvana Čepelak
AuthorDubravka Čvorišćec
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medical biochemistry and haematology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Medical Biochemistry
Abstract (croatian)
Makroenzimi su kompleksi normalnih enzima ili izoenzima nastalih vlastitom polimerizacijom, najčešće povezivanjem s imunoglobulinima, zatim nekim li-poproteinima, proteinima ili fragmentima staničnih membrana. U pravilu su veće molekularne mase i dužeg poluživota u sistemskoj cirkulaciji. Pojava mak-roenzima u serumu može se odraziti na analitički proces mjerenja aktivnosti enzima te biti uzrokom pogrešne interpretacije povećane aktivnosti enzima zbog slabog razumijevanja kliničkog značenja prisutnosti makroenzima.
Abstract (english)
Macroenzymes are complexes consisting of normal enzymes or isoenzymes generated by their polymerization, mostly by their linking to immunoglobu-lins, some lipoproteins, proteins, or cell membrane fragments. Generally, macroenzymes are characterized by a greater molecular mass and longer half-life in systemic circulation. The occurrence of macroenzymes in serum may influence analytical measurement of an enzyme activity or may cause erroneous interpretation of elevated enzyme activity due to inadequate understanding of the clinical relevance of the presence of macroenzymes.
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiochemia Medica
Numberingvol. 17, no. 1, pp. 52-59
p-ISSN1330-0962
e-ISSN1846-7482
URN:NBNurn:nbn:hr:163:017429
Publication2007
Document URLhttps://hrcak.srce.hr/12862
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-10 15:25:29