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master's thesis
Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. urn:nbn:hr:163:997085
Bakalović, Paula
University of Zagreb
Faculty of Pharmacy and Biochemistry

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Bakalović, P. (2015). Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:997085

Bakalović, Paula. "Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:997085

Bakalović, Paula. "Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:997085

Bakalović, P. (2015). 'Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 23 December 2024, https://urn.nsk.hr/urn:nbn:hr:163:997085

Bakalović P. Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2015 [cited 2024 December 23] Available at: https://urn.nsk.hr/urn:nbn:hr:163:997085

P. Bakalović, "Primjena potencijalno neprikladnih lijekova u osoba starije životne dobi", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:163:997085

Metadata
TitlePrimjena potencijalno neprikladnih lijekova u osoba starije životne dobi
Title (english)Potentially inappropriate medication use in the elderly
AuthorPaula Bakalović
MentorVesna Bačić Vrca (mentor)
Committee memberVesna Bačić Vrca
Committee memberMario Jug
Committee memberJelena Filipović-Grčić
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
Zagreb
Defense date and country2015-09-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Neprikladno propisivanje lijekova starijim osobama je često povezano s povećanim rizikom za nastanak neželjenih djelovanja lijekova, povećanim morbiditetom i mortalitetom, te troškovima zdravstvene zaštite. Cilj ove studije bio je odrediti učestalost propisivanja potencijalno neprikladnih lijekova (PNL) osobama starije životne dobi koristeći originalni protokol razvijen od autora Mimica Matanović and Vlahović-Palčevski. Istraživanje je uključilo 102 hospitalizirana bolesnika starosti 2: 65 godina. Glavni izvor podataka bila je medicinska dokumentacija bolesnika. Prosječna dob bila je 74 godine (raspon 65 - 92), a prosječan broj lijekova po ispitaniku bio je 6 (raspon 1 - 15). Ukupno je 40,2 % bolesnika uzimalo barem jedan PNL. Najčešći PNL bili su dugodjelujući benzodiazepini, centralni antihipertenziv moksonidin i nesteroidni anti-inflamatomi lijekovi (NSAIL). Barem jedna kombinacija lijekova koji mogu stupiti u klinički značajnu inetrakciju bila je propisana 38,2 % bolesnika. Najčešće kombinacije s uključivale su primjenu NSAIL i antihipertenziva ili diuretika, istovremenu primjenu više lijekova s učinkom na SŽS i kombinacije lijekova koje mogu rezultirati hiperkalijemijom. Ovim istraživanjem otkrivena je velika prevalencija neodgovarajućeg propisivanja lijekova osobama starije životne dobi.
Abstract (english)
Inappropriate prescribing to the elderly is often associated with an increased risk od adverse drug events, morbidity, mortality and health care costs. The purpose of this study was to determine the prevalence of potentially inappropriate medication use in the elderly using the new comprehensive protocol developed by authors Mimica Matanović and Vlahović-Palčevski. The study included 102 hospitalized patients aged ~ 65 years. Information on prescribed drugs was retrieved mainly from the patients' medical records. The average age of the patient was found to be 74 years (range 65 - 92), and each patient was on an average of 6 medicines (range 1 - 15). A total of 40,2 % of patients received at least one potentially inappropriate medication. Drugs of most concem were long-acting benzodiazepines, centrally active antihypertensive moxonidine and nonsteroidal antiinflammatory drugs (NSAIDs). A total of 38,2 % of patients were prescribed at least one drug combination that is potentially harmful. The most common combinations included NSAID and an antihypertensive or diuretic, simultaneous use of CNS agents and combination of drugs which can lead to severe hyperkalemia. This study has shown that inappropriate prescribing to older people is highly prevalent.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:997085
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-02-18 10:38:06