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Scientific paper - Original scientific paper
Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution
Croatica Chemica Acta, 56 (1983), 1; 61-77. urn:nbn:hr:163:697896
Biruš, Mladen; Bradić, Zdravko; Kujundžić, Nikola; Pribanić, Marijan

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Biruš, M., Bradić, Z., Kujundžić, N. & Pribanić, M. (1983). Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution. Croatica Chemica Acta, 56. (1), 61-77. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:697896

Biruš, Mladen, et al. "Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution." Croatica Chemica Acta, vol. 56, no. 1, 1983, pp. 61-77. https://urn.nsk.hr/urn:nbn:hr:163:697896

Biruš, Mladen, Zdravko Bradić, Nikola Kujundžić and Marijan Pribanić. "Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution." Croatica Chemica Acta 56, no. 1 (1983): 61-77. https://urn.nsk.hr/urn:nbn:hr:163:697896

Biruš, M., et al. (1983) 'Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution', Croatica Chemica Acta, 56(1), pp. 61-77. Available at: https://urn.nsk.hr/urn:nbn:hr:163:697896 (Accessed 27 December 2024)

Biruš M, Bradić Z, Kujundžić N, Pribanić M. Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution. Croatica Chemica Acta [Internet]. 1983 [cited 2024 December 27];56(1):61-77. Available at: https://urn.nsk.hr/urn:nbn:hr:163:697896

M. Biruš, Z. Bradić, N. Kujundžić and M. Pribanić, "Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution", Croatica Chemica Acta, vol. 56, no. 1, pp. 61-77, 1983. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:697896. [Accessed: 27 December 2024]

Metadata
Title (english)Kinetics and mechanism of interactions between iron(lll) and desferrioxamine B. The formation and hydrolysis of ferrioxamine B in acidic aqueous solution
AuthorMladen Biruš
AuthorZdravko Bradić
MBZ: 5132
AuthorNikola Kujundžić
AuthorMarijan Pribanić
MBZ: 38805
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of analytical chemistry)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of general and inorganic chemistry)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract (english)
The kinetics of the formation and hydrolysis of ferrioxamine B complexes have been studied in acidic aqueous solution (0.001- -1.0 M HCl) at 25.0 °c, μ = 1.0 M (maintained by NaCl). Two stage kinetics have been observed in both the formation and in the hydrolysis reactions. The proposed reaction model involves formation/ hydrolysis of bidentate, tetradentate, and hexadentate bonded desferrioxamine B to iron(III). The formation of the bidentate complex occurs by two paths: one involving unhydrolysed ferric ion yields the rate constant k1 = 282 M-1 s-1, and the other via hydrolysed ferric species gives the rate constant k1' = 4.1 X 103· M-1 s-1• The analogous rate constants for the reverse hydrolysis reactions were obtained; k - 1 = = 0.65 M-1 s-1 for the acid dependent and k _ 1' = 0.016 s·1 for the acid independent path. The formation and hydrolysis rate constants of the tetradentate linked complex have been calculated using the steady-state approximation as k 2 = 9 s·1 and k _2 = 2 M-1 s-1, respectively. The conversion of tetradentate to hexadentate as well as hydrolysis of the hexadentate to tetradentate bonded species have been characterized by the rate constants k 3 = 2.2 s-1 and k _ 3 = = 18 M-1 s-1, respectively. These results are compared with kinetic data previously reported. Chloride media increases the rate of formation and hydrolysis of the bidentate species, and possibly has the same effect on the tetradentate species but does not affect hydrolysis of the hexadentate complex. These effects were analyzed in terms of a labilization of iron(III) coordinated ligands by inner-sphere coordinated chloride.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 56, no. 1, pp. 61-77
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:697896
Publication1983
Document URLhttps://hrcak.srce.hr/194241
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-05-05 11:15:47