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Mitotoksičnost inducirana lijekovima
Farmaceutski glasnik, 74 (2018), 7-8; 513-530. urn:nbn:hr:163:728966
Petrić, Zvonimir; Žuntar, Irena

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Petrić, Z. & Žuntar, I. (2018). Mitotoksičnost inducirana lijekovima. Farmaceutski glasnik, 74. (7-8), 513-530. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:728966

Petrić, Zvonimir and Irena Žuntar. "Mitotoksičnost inducirana lijekovima." Farmaceutski glasnik, vol. 74, no. 7-8, 2018, pp. 513-530. https://urn.nsk.hr/urn:nbn:hr:163:728966

Petrić, Zvonimir and Irena Žuntar. "Mitotoksičnost inducirana lijekovima." Farmaceutski glasnik 74, no. 7-8 (2018): 513-530. https://urn.nsk.hr/urn:nbn:hr:163:728966

Petrić, Z. and Žuntar, I. (2018) 'Mitotoksičnost inducirana lijekovima', Farmaceutski glasnik, 74(7-8), pp. 513-530. Available at: https://urn.nsk.hr/urn:nbn:hr:163:728966 (Accessed 22 November 2024)

Petrić Z, Žuntar I. Mitotoksičnost inducirana lijekovima. Farmaceutski glasnik [Internet]. 2018 [cited 2024 November 22];74(7-8):513-530. Available at: https://urn.nsk.hr/urn:nbn:hr:163:728966

Z. Petrić and I. Žuntar, "Mitotoksičnost inducirana lijekovima", Farmaceutski glasnik, vol. 74, no. 7-8, pp. 513-530, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:728966. [Accessed: 22 November 2024]

Metadata
Title (croatian)Mitotoksičnost inducirana lijekovima
AuthorZvonimir Petrić
AuthorIrena Žuntar
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Purpose of this review paper is to point out induced mechanisms of mitochondrial dysfunction associated with common use of well-known therapeutics and xenobiotics. Drug-induced mitotoxicity can occur by several mechanisms. They can involve inhibition of mitochondrial respiratory chain, an induction of mitochondrial oxidative stress and generating reactive oxygen species, an impairment of oxidative phosphorylation and ATP synthesis, an impairment of mitochondrial membrane integrity and structure or a disruption in the mitochondrial genome. Nowadays, drug-induced mitotoxicity is an important challenge for many pharmacologists and toxicologists who are trying to develop strategies for minimizing adverse drug reactions aiming to give contribution to modern pharmacotherapy.
Keywords (croatian)
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 74, no. 7-8, pp. 513-530
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:728966
Publication2018
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-06-16 13:44:36