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Scientific paper - Original scientific paper
Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu
Farmaceutski glasnik, 69 (2013), 5; 319-331. urn:nbn:hr:163:834051
Vidić Štrac, Ivona; Žuntar, Irena; Dimitrov, Nino; Puklek, Maja

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Vidić Štrac, I., Žuntar, I., Dimitrov, N. & Puklek, M. (2013). Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu. Farmaceutski glasnik, 69. (5), 319-331. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:834051

Vidić Štrac, Ivona, et al. "Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu." Farmaceutski glasnik, vol. 69, no. 5, 2013, pp. 319-331. https://urn.nsk.hr/urn:nbn:hr:163:834051

Vidić Štrac, Ivona, Irena Žuntar, Nino Dimitrov and Maja Puklek. "Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu." Farmaceutski glasnik 69, no. 5 (2013): 319-331. https://urn.nsk.hr/urn:nbn:hr:163:834051

Vidić Štrac, I., et al. (2013) 'Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu', Farmaceutski glasnik, 69(5), pp. 319-331. Available at: https://urn.nsk.hr/urn:nbn:hr:163:834051 (Accessed 26 November 2024)

Vidić Štrac I, Žuntar I, Dimitrov N, Puklek M. Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu. Farmaceutski glasnik [Internet]. 2013 [cited 2024 November 26];69(5):319-331. Available at: https://urn.nsk.hr/urn:nbn:hr:163:834051

I. Vidić Štrac, I. Žuntar, N. Dimitrov and M. Puklek, "Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu", Farmaceutski glasnik, vol. 69, no. 5, pp. 319-331, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:834051. [Accessed: 26 November 2024]

Metadata
Title (croatian)Etilenglikol i dietilenglikol u zubnim pastama na hrvatskom tržištu
AuthorIvona Vidić Štrac
AuthorIrena Žuntar
AuthorNino Dimitrov
AuthorMaja Puklek
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Diethylene glycol (DEG) (CAS 111-46-6) is a highly toxic organic solvent that may cause nausea, dizziness, kidney failure, breathing problems, convulsions and even coma when ingested The potential health risks from chronic exposure to DEG are a particular concern in specific vulnerable populations such as children and consumers with kidney or liver disease. DEG is forbidden as cosmetic ingredient but can be present as an impurity in glycerol and polyethylene glycols, common ingredients in oral care products. Maximum permitted concentration as impurity is 0.1 % m/m. the objective of this study was to determine the presence of diethylene glycol in toothpaste on the Croatian market using a gas chromatography-mass spectrometry method. Linearity of the response of mass detector was tested by analyzing standard solutions with increasing concentrations of ethylene glycol (EG) and diethylene glycol. Regression analysis of chromatographic data indicates that linearity of response in the detector was within the examined concentration area 0.5-50 mg/L, with correlation coefficients >0.998. Limit of detection (LOD) far DEG was < 6 mg/kg, and far EG < 4 mg/kg. Testing was conducted on 30 samples of toothpaste produced and marketed in Croatia and EU. Obtained results were significantly below the permitted threshold of 0.1 % thus assuring consumer safety.
Keywords (croatian)
Languagecroatian
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 69, no. 5, pp. 319-331
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:834051
Publication2013
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-07-07 13:34:33