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Scientific paper - Original scientific paper
Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)
Farmaceutski glasnik, 64 (2008), 6; 299-308. urn:nbn:hr:163:487694
Zovko, Marijana; Kosalec, Ivan; Kalođera, Zdenka; Pepljnjak, Stjepan; Todorić-Kovačević, Vesna

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Zovko, M., Kosalec, I., Kalođera, Z., Pepljnjak, S. & Todorić Kovačević, V. (2008). Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium). Farmaceutski glasnik, 64. (6), 299-308. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:487694

Zovko, Marijana, et al. "Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)." Farmaceutski glasnik, vol. 64, no. 6, 2008, pp. 299-308. https://urn.nsk.hr/urn:nbn:hr:163:487694

Zovko, Marijana, Ivan Kosalec, Zdenka Kalođera, Stjepan Pepljnjak and Vesna Todorić Kovačević. "Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)." Farmaceutski glasnik 64, no. 6 (2008): 299-308. https://urn.nsk.hr/urn:nbn:hr:163:487694

Zovko, M., et al. (2008) 'Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)', Farmaceutski glasnik, 64(6), pp. 299-308. Available at: https://urn.nsk.hr/urn:nbn:hr:163:487694 (Accessed 22 November 2024)

Zovko M, Kosalec I, Kalođera Z, Pepljnjak S, Todorić Kovačević V. Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium). Farmaceutski glasnik [Internet]. 2008 [cited 2024 November 22];64(6):299-308. Available at: https://urn.nsk.hr/urn:nbn:hr:163:487694

M. Zovko, I. Kosalec, Z. Kalođera, S. Pepljnjak and V. Todorić Kovačević, "Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)", Farmaceutski glasnik, vol. 64, no. 6, pp. 299-308, 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:487694. [Accessed: 22 November 2024]

Metadata
Title (croatian)Sastav i antioksidativna aktivnost etanolnog ekstrakta medvjetkina lista (Uvae ursi folium)
AuthorMarijana Zovko
AuthorIvan Kosalec
AuthorZdenka Kalođera
AuthorStjepan Pepljnjak
AuthorVesna Todorić-Kovačević
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of microbiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Abstract (english)
Bearberry leaf is a drug frequently used in treatment of urological infections. Ethanolic extract of bearberry leaf was prepared by ultrasonication. Phenolic composition of the extract was compared to the composition of drug. The study has revealed that both, bearberry leaf and its ethanolic extract, are rich in phenolic compounds that make 65. 95% and 22. 77% of their weight, respectively. Extract and drug contain 21. 00% and 6.26%, of phenolic glycosides, as well as 22. 77% and 11.83% tannins, respectively. Phenolic glicosides to tannins ratio is notably higher in the extract, pointing to possible reduction in side effects with use of extract instead of drug. Furthermore, antioxidanr activity of the extract was determined and compared to activity of synthetic antioxidant butylated hydroxyanisol (BHA). Antioxidant activity was determined by three methods: reducing power, reactivity with 2,2-diphenyl-l-pycrilhydrazyl (DPPH) free radical and /3-carotene-linoleate assay. The extract was an effective antioxidant in all the tests employed, especially as scavenger of DPPH free radical, as well as in /3-carotene-linoleate assay, where no statistically significant difference between activity of bearberry leaf extract and BHA could be observed (p>0,05).
Keywords (croatian)
Languagecroatian
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 64, no. 6, pp. 299-308
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:487694
Publication2008
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-09-30 13:09:02