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Professional paper - Review paper
Najnovije spoznaje u istraživanju inhibitora aromataze
Farmaceutski glasnik, 65 (2009), 10; 557-565. urn:nbn:hr:163:316740
Bojić, Mirza; Medić-Šarić, Marica

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Bojić, M. & Medić Šarić, M. (2009). Najnovije spoznaje u istraživanju inhibitora aromataze. Farmaceutski glasnik, 65. (10), 557-565. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:316740

Bojić, Mirza and Marica Medić Šarić. "Najnovije spoznaje u istraživanju inhibitora aromataze." Farmaceutski glasnik, vol. 65, no. 10, 2009, pp. 557-565. https://urn.nsk.hr/urn:nbn:hr:163:316740

Bojić, Mirza and Marica Medić Šarić. "Najnovije spoznaje u istraživanju inhibitora aromataze." Farmaceutski glasnik 65, no. 10 (2009): 557-565. https://urn.nsk.hr/urn:nbn:hr:163:316740

Bojić, M. and Medić Šarić, M. (2009) 'Najnovije spoznaje u istraživanju inhibitora aromataze', Farmaceutski glasnik, 65(10), pp. 557-565. Available at: https://urn.nsk.hr/urn:nbn:hr:163:316740 (Accessed 27 December 2024)

Bojić M, Medić Šarić M. Najnovije spoznaje u istraživanju inhibitora aromataze. Farmaceutski glasnik [Internet]. 2009 [cited 2024 December 27];65(10):557-565. Available at: https://urn.nsk.hr/urn:nbn:hr:163:316740

M. Bojić and M. Medić Šarić, "Najnovije spoznaje u istraživanju inhibitora aromataze", Farmaceutski glasnik, vol. 65, no. 10, pp. 557-565, 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:316740. [Accessed: 27 December 2024]

Metadata
Title (croatian)Najnovije spoznaje u istraživanju inhibitora aromataze
AuthorMirza Bojić
AuthorMarica Medić-Šarić
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Most of the therapeutics used in chemotherapy are non selective drugs that act non specifically, effecting healthy tissue and causing serious side effects (depression of bone marrow, nausea, hair loss etc.). Every day new macromolecular targets are discovered. One of very important targets in therapy of breast cancer is aromatase - CYP enzyme unique for its function of converting male into female hormones. This paper is focused to the enzyme and its mechanism of action, as this was explained very recently. Physiology and patophysiology of aromatase is explained, as the basis for understanding action of aromatase inhibitors. Special attention is devoted to expression of aromatase and potential use of selective modulators of aromatase, as well as new indications of aromatase inhibitors.
Keywords (croatian)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 65, no. 10, pp. 557-565
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:316740
Publication2009
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-10-01 09:39:38