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Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova
Farmaceutski glasnik, 54 (1998), 2; 37-51. urn:nbn:hr:163:109839
Medić-Šarić, Marica; Franić, Danijela; Debeljak, Željko

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Medić Šarić, M., Franić, D. & Debeljak, Ž. (1998). Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova. Farmaceutski glasnik, 54. (2), 37-51. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:109839

Medić Šarić, Marica, et al. "Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova." Farmaceutski glasnik, vol. 54, no. 2, 1998, pp. 37-51. https://urn.nsk.hr/urn:nbn:hr:163:109839

Medić Šarić, Marica, Danijela Franić and Željko Debeljak. "Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova." Farmaceutski glasnik 54, no. 2 (1998): 37-51. https://urn.nsk.hr/urn:nbn:hr:163:109839

Medić Šarić, M., Franić, D. and Debeljak, Ž. (1998) 'Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova', Farmaceutski glasnik, 54(2), pp. 37-51. Available at: https://urn.nsk.hr/urn:nbn:hr:163:109839 (Accessed 26 December 2024)

Medić Šarić M, Franić D, Debeljak Ž. Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova. Farmaceutski glasnik [Internet]. 1998 [cited 2024 December 26];54(2):37-51. Available at: https://urn.nsk.hr/urn:nbn:hr:163:109839

M. Medić Šarić, D. Franić and Ž. Debeljak, "Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova", Farmaceutski glasnik, vol. 54, no. 2, pp. 37-51, 1998. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:109839. [Accessed: 26 December 2024]

Metadata
Title (croatian)Lipofilnost lijekova. I. dio: Važnost lipofilnosti u istraživanju novih lijekova
AuthorMarica Medić-Šarić
AuthorDanijela Franić
AuthorŽeljko Debeljak
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Lipophilicity is a prime physicochemical descriptor of xenobiotics with relevance to their biological properties. The hydrophobic interaction of drugs with a receptor and the toxicological properties are examples of a steadily increasing number of topics in which lipophilicity plays an important role. A number of empirical and theoretical approach have been developed during the last twenty years for calculation of log P values. The most common experimental method for determining the equilibria of drugs partitioning between water and n-octanol is shake-flask method. In this context calculative approaches are superior to experimental procedures.
Keywords (croatian)
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 54, no. 2, pp. 37-51
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:109839
Publication1998
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-03-05 10:42:30