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master's thesis
Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. urn:nbn:hr:163:469363
Ritoša, Klara
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Ritoša, K. (2018). Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:469363

Ritoša, Klara. "Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:469363

Ritoša, Klara. "Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:469363

Ritoša, K. (2018). 'Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 30 December 2024, https://urn.nsk.hr/urn:nbn:hr:163:469363

Ritoša K. Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2018 [cited 2024 December 30] Available at: https://urn.nsk.hr/urn:nbn:hr:163:469363

K. Ritoša, "Fitopreparati u terapiji akni, melazme i seboroičnog dermatitisa", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:163:469363

Metadata
TitleFitopreparati u terapiji akni, melazme i seboroičnog dermatitisa
Title (english)Phytopreparations in therapy acne, melasma and seborrheic dermatitis
AuthorKlara Ritoša
MentorMarijana Zovko Končić (mentor)
Committee memberMarijana Zovko Končić (predsjednik povjerenstva)
Committee memberJasna Jablan (član povjerenstva)
Committee memberSuzana Inić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Zagreb
Defense date and country2018-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Kožna oboljenja poput akni, melazme i seboroičnog dermatitisa predstavljaju zdravstveni i psihosocijalni problem. Za tretiranje navedenih oboljenja koriste se mnoge biljne vrste, ali samo su za rijetke provedene kliničke studije. U ovom radu navedeni su preparati koji se najčešće preporučuju u terapiji akni, melazme i seboroičnog dermatitisa na hrvatskom tržištu. Nadalje, navedene su njihove biljne sastavnice i provedena klinička istraživanja, ukoliko postoje. U terapiji akni od biljnih vrsta učinak pokazuju aloe vera gel, terpenofenol bakuhiol iz biljnih vrsta Cullen corylifolium i Otholobium pubescens u kombinaciji s ekstraktom ginka, emulzija zelenog čaja, 5% eterično ulje čajevca, ulje jojobe u lokalnoj primjeni te sjemenke grožđa i ulje noćurak per os. Aloe vera u liposomima, bisabolol iz kamilice, ekstrakt sladić, ekstrakt ploda indijskog ogrozda, belides (komercijalni ekstrakt tratinčice), peršin i ekstrakt sjemenki grožđa (peroralno) imali su obečavajući učinak na smanjenje simptoma melazme, dok ekstrakt soje nije pokazao značajan učinak. Kod smanjenja simptoma seboroičnog dermatitisa pomogli su pripravci s aloe verom, kod prhuti šampon s eteričnim uljem čajevca i otopina s mirtom, a ulju noćurka pokazuje blagi učinak. U preparatima na našem tržištu prisutne su kombinacije biljnih vrsta, a nije poznato kakav učinak imaju zajedno. Provedene kliničke studije upućuju na to da bi biljni preparati mogli pospješiti djelovanje ili smanjiti nuspojave standardne terapije, te da bi neki među njima mogli i ravnopravno konkurirati lijekovima standardne medicine. Ipak, potrebno je provesti još mnogo dobro dizajniranih kliničkih ispitivanja kako bi se detaljno i objektivno procijenila njihova učinkovitost i nuspojave te kako bi ljekarnici mogli savjetovati pacijentima što bolji proizvod i provoditi farmaciju temeljenu na dokazima.
Abstract (english)
Skin deseases such as acne, melasma and seborrheic dermatitis represent health and psychosocial problem. Many plant species have been used in treating these deseases, but only a few have clinical studies. This tesis includes most commonly recomended preparations in treating of acne, melasma and seborrheic dermatitis in the Croatian market, as well as its herbal components and clinical studies conduceted with them. Promising effects in acne therapy are shown by aloe vera gel, terpenophenol bakuchiol from Cullen corylifolium i Otholobium pubescens in combination with ginko extract, green tea emulsion, 5% tea tree oil, jojoba oil in local therapy and grape seeds extract as well as primrose oraly. Aloe vera within liposome fraction, bisabolol from chamomile, liquorice extract, belides (commercial daisy extract), Phyllanthus emblica fruit extract, parsley and grape seeds extract had a promising effect in alleviating simptoms of melasma while soy extract had no significant effect. In alleviating simptoms of seborrheic dermatitis preparations with aloe vera helped, for dandruff were preparations with tea tree oil and myrtle solution while primrose oil has shown mild effect. The preparations found in Croatian market are a combination of plant species, but its mutual effects are still unknown. Clinical studies indicate that some herbal preparations may increase activity or reduce side-effects of standard therapy, or even be equally efficient as the drugs from conventional medicine. However, new, well designed clinical trials are needed to allow a detailed and objective evaluation of their activity. In addition, such studies would give the pharmacists the posssiblilty to advise the use of the best products to their patients as well as to practice evidence-based pharmacy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:469363
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-04-21 12:27:40