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master's thesis
Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. urn:nbn:hr:163:951455
Komšić, Karla
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of medicinal chemistry
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of physical chemistry

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Komšić, K. (2019). Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:951455

Komšić, Karla. "Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry; University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:951455

Komšić, Karla. "Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry; University of Zagreb, Faculty of Pharmacy and Biochemistry, 2019. https://urn.nsk.hr/urn:nbn:hr:163:951455

Komšić, K. (2019). 'Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry; University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 27 August 2024, https://urn.nsk.hr/urn:nbn:hr:163:951455

Komšić K. Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2019 [cited 2024 August 27] Available at: https://urn.nsk.hr/urn:nbn:hr:163:951455

K. Komšić, "Određivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:163:951455

Metadata
TitleOdređivanje biomedicinskih važnih fenolnih spojeva u maslinovom ulju i plodu masline
Title (english)Determination of biomedically important phenolic compounds in olive oil and fruit
AuthorKarla Komšić
MentorMonika Barbarić (mentor)
MentorAna Karković Marković (mentor)
Committee memberMonika Barbarić (predsjednik povjerenstva)
Committee memberCvijeta Jakobušić Brala (član povjerenstva)
Committee memberAna Karković Marković (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Zagreb
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of physical chemistry)
Zagreb
Defense date and country2019-09-26, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Cilj ovog rada bio je određivanje biomedicinski važnih fenolnih spojeva u maslinovom ulju i plodu masline kultivara Oblica. Nakon ekstrakcije, provedena je HPLC DAD analiza uzoraka na valnoj duljini od 278 nm te su utvrđene koncentracije fenolnih spojeva u ulju masline: 20,6 mg/kg ulja hidroksitirozola, 8,36 mg/kg ulja tirozola i 304 mg/kg ulja oleaceina, U plodu masline određene su koncentracije 215 mg/kg ploda hidroksitirozola, 61 mg/kg ploda tirozola i 272 mg/kg ploda oleuropeina. Prisutnost ovih polifenola u ulju i plodu masline ukazuje na prednosti mediteranske prehrane za ljudsko zdravlje i nudi potencijalna farmakološka rješenja u smjeru antioksidativnog, protuupalnog i antitumorskog učinka
Abstract (english)
The aim of this work was quantitative analysis of biomedically import ant phenolic compounds in olive oil and fruit in Croatian cultivar Oblica. Aft er extraction, HPLC DAD analysis was carried out with the apsorption of eluates detected on 278 nm with following results: 20,6 mg hydroxytyrosol, 8,36 mg tyrosol an d 304 oleacein per kg of oil and 215 mg hydroxytyrosol, 60,9 mg tyrosol and 272 mg of oleuropein per kg of fruit. Presence of these polyphenols with various biological properties emphasizes the advantages of Mediterranean diet. In addition, it offers new pharmacological possibilities due to its antioxidative, anti inflammatory and anticancer effects.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:951455
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-04-22 13:53:56