Flu is one of the most prevalent diseases globally. It affects around one billion of the world's population annually, causing dangerous complications in 3 to 5 million cases, resulting in 290 000 to 650,000 deaths. It is difficult for the human immune system to acquire complete immunity to the virus because it constantly changes its antigenic structure. This poses a major problem both in the development of antiviral drugs, in which the presence of resistance to action is significant, and in the development of vaccines, which are tailored each year to the expected circulating strain. Vaccination remains the most effective method of combating influenza virus, and is especially recommended for at-risk groups. Unfortunately, vaccination coverages are very low in the world. In order to increase coverage, many countries have implemented the possibility of influenza immunization in public pharmacies in recent years, a such actions have proved positive. The Republic of Croatia is not an exception to the low coverage rates, and vaccination against influenza in public pharmacies is not legally possible. This paper examines the opinion of Croatian citizens on influenza vaccination in pharmacies and also examines the consequences of the potential implementation of such a practice. The survey was conducted through an online and printed questionnaire. The representativeness of the sample is questionable. The respondents' past was examined in the form of influenza vaccination and the expected behavior in the case of pharmacy vaccination implementation. The results are positive in all categories of subjects and, within the various subpopulations in the examined sample, increase in influenza coverage in the range of 13.33 - 17.07% is estimated. The paper also examined the properties of the test sample. One third of the respondents were found not to consider vaccines necessary for public health protection, which indicates the need for better education of citizens. Higher anti-vaccination attitudes have been found in coastal Croatian, middle-aged, female respondents, and respondents with lower-levels of education. Persons with a tendency to take seasonal vaccination were found to have more confidence in the pharmacist as a healthcare professional. Based on the results of this paper, the profession should consider conducting statistically stronger research in order to undoubtedly determine the rate of citizens' confidence in Croatian pharmacists.