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professional thesis
Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. urn:nbn:hr:163:127816
Dizdar, Ružica
University of Zagreb
Faculty of Pharmacy and Biochemistry

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Dizdar, R. (2022). Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19 (Professional thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:127816

Dizdar, Ružica. "Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:127816

Dizdar, Ružica. "Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:127816

Dizdar, R. (2022). 'Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19', Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 24 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:127816

Dizdar R. Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19 [Professional thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2022 [cited 2024 November 24] Available at: https://urn.nsk.hr/urn:nbn:hr:163:127816

R. Dizdar, "Upotreba postojećih lijekova u farmakoterapiji bolesti COVID-19", Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:163:127816

Metadata
TitleUpotreba postojećih lijekova u farmakoterapiji bolesti COVID-19
AuthorRužica Dizdar
MentorIveta Šimić (mentor)
Committee memberMaja Ortner Hadžiabdić (predsjednik povjerenstva)
Committee memberIveta Šimić (član povjerenstva)
Committee memberVesna Bačić Vrca (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
Zagreb
Defense date and country2022, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Cilj istraživanja: Cilj ovog rada je pregledno prikazati glavne specifičnosti primjene određenih postojećih lijekova u farmakoterapiji COVID-19. Ispitanici i metode: U tu svrhu korištena je najnovija znanstvena i stručna literatura, trenutno važeće terapijske smjernice, publikacije stručnih udruga i institucija, baza lijekova Agencije za lijekove i medicinske proizvode i Europske agencije za lijekove te drugi raspoloživi izvori. Rezultati: Pregledno su prikazani lijekovi koji se trenutno najčešće koriste u ublažavanju simptoma i liječenju COVID-19: monoklonska protutijela, kortikosteroidi, antivirotici te ostali lijekovi. Zaključak: Primjena postojećih lijekova koji su se u ovoj pandemiji počeli koristiti u svrhu liječenja COVID-19 od samog početka pokazala se izazovnom. Unatoč složenoj situaciji s kojom su se kliničari susreli i dalje je ostalo jednako važno voditi brigu o dovoljnoj količini relevantnih znanstvenih dokaza koji bi opravdali primjenu tih lijekova u liječenju ove bolesti. Također, važno je i spriječiti situaciju u kojoj bi takva primjena postojećih lijekova mogla dovesti do nestašice za pacijente koji su ih koristili u do sada odobrenim indikacijama te dodatne opterećenosti zdravstvenog sustava koji bi nastao kao posljedica toga. Dobro poznavanje kliničkih manifestacija bolesti i općenito patofiziologije COVID-19 je važno za odluku o ključnim parametrima koji definiraju učinak farmakoterapije: vrijeme primjene lijeka (s obzirom na stadij uznapredovalosti bolesti) i vrsta lijeka. Magistri farmacije, kao visokoobrazovani stručnjaci koji posjeduju široko znanje o mehanizmu djelovanja lijekova, mogu pomoći identificirati terapijske probleme te doprinijeti pozitivnim ishodima liječenja.
Abstract (english)
The goal of this research: The goal of this thesis is to present the main aspects of the use of some of the existing medications in COVID-19 pharmacotherapy. Research methods: For this purpose, a variety of latest scientific and professional literature, current guidelines, publications by professional associations and institutions, the Croatian Agency for Medicinal Products and Medical Devices database, the European Medicines Agency database and other available sources were examined. Results: Most commonly used medications (to this moment) for treating COVID-19: monoclonal antibodies, corticosteroids, antivirotics and others were presented in one place. Conclusion: From the very beginning of this pandemic the use of existing medications for treating COVID-19 has proved to be very challenging. Despite the complex situation clinicians had to face, it is still important to provide a sufficient amount of relevant scientific evidence to justify the use of these medications in the treatment of this disease. It is also important to prevent a situation in which such use of existing medications could lead to shortages for patients who have used them in so far approved indications. This could also be an additional burden on the healthcare system. Good knowledge of the clinical manifestations and pathophysiology of COVID-19 in general is important to decide on the key parameters that define the effect of the pharmacotherapy: the time of drug administration (with respect to the stage of disease progression) and the type of drug. Pharmacists, as highly educated experts who have extensive knowledge of the mechanism of action of drugs, can help identify therapeutic problems and contribute to positive outcome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:127816
Study programmeTitle: Clinical pharmacy
Study programme type: university
Study level: postgraduate specialist
Academic / professional title: sveučilišni/a magistar/sveučilišna magistra kliničke farmacije (sveučilišni/a magistar/sveučilišna magistra kliničke farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-06-02 15:45:21