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master's thesis
Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2020. urn:nbn:hr:163:035724
Radman, Iva
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Radman, I. (2020). Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L. (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:035724

Radman, Iva. "Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2020. https://urn.nsk.hr/urn:nbn:hr:163:035724

Radman, Iva. "Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2020. https://urn.nsk.hr/urn:nbn:hr:163:035724

Radman, I. (2020). 'Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 21 December 2024, https://urn.nsk.hr/urn:nbn:hr:163:035724

Radman I. Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L. [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2020 [cited 2024 December 21] Available at: https://urn.nsk.hr/urn:nbn:hr:163:035724

I. Radman, "Određivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:163:035724

Metadata
TitleOdređivanje sadržaja arbutina i trjeslovina u listu brusnice, Vaccinium vitis idaea L.
Title (english)Determination of arbutin and tannin content in lingonberry leaf, Vaccinium vitis idaea L.
AuthorIva Radman
MentorMaja Bival Štefan (mentor)
Committee memberMaja Bival Štefan (predsjednik povjerenstva)
Committee memberMarijana Zovko Končić (član povjerenstva)
Committee memberJasna Jablan (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Zagreb
Defense date and country2020-09-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
U okviru ovog diplomskog rada provedena je analiza arbutina i trjeslovina u čajevima od listova vrste Vaccinium vitis-idaea (Ericaceae), tj. brusnice. Kvantifikacija arbutina provedena je koristeći farmakopejske metode, UV-Vis spektrofotometriju i tekućinsku kromatografiju visoke djelotvornosti, za određivanje derivata hidrokinona. Čaj od lista brusnice proizvođača Suban sadržava najveći udio hidrokinonskih derivata od svih uzoraka u iznosu od 5,94 % (na 455 nm prema metodi) izraženih kao arbutin, dok čaj proizvođača Agristar omogućuje unos najviše dnevne doze arbutina u iznosu od 251,10 mg. Kvantifikacija trjeslovina provedena je farmakopejskom metodom UV-Vis spektrofotometrije za određivanje trjeslovina. Čaj od lista brusnice proizvođača Suban sadržava najveći udio trjeslovina od svih uzoraka u iznosu od 4,18 % (na 760 nm prema metodi) izraženih kao pirogalol. Rezultati upućuju na to da brusnica ima potencijal za korištenje u liječenju urinarnih infekcija s lakšim i manje učestalim gastrointestinalnim nuspojavama u odnosu na list medvjetke.
Abstract (english)
As part of this diploma thesis, an analysis of arbutin and tannins in teas made from the leaves of the species Vaccinium vitis-idaea (Ericaceae), ie lingonberries, was performed. Quantification of arbutin was performed using pharmacopoeial methods, UV-Vis spectrophotometry and high performance liquid chromatography, for the determination of hydroquinone derivatives. Suban’s lingonberry leaf tea contains the highest proportion of hydroquinone derivatives of all samples in the amount of 5.94% (455 nm according to the method) expressed as arbutin, while Agristar’s tea allows the intake of the highest daily dose of arbutin in the amount of 251.10 mg. Quantification of tannins was performed by pharmacopoeial method of UV-Vis spectrophotometry for the determination of tannins. Suban’s lingonberry leaf tea contains the most tannins of all samples and this was 4.18 % (760 nm according to the method) expressed as pyrogallol. The results suggest that lingonberry has the potential for use in the treatment of urinary tract infections with milder and less frequent gastrointestinal side effects compared to bearberry leaf.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:035724
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2022-09-15
Terms of useLicence In copyright icon
Created on2022-08-30 13:33:34