prikaz prve stranice dokumenta Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva
Embargo period 2024-09-02
master's thesis
Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. urn:nbn:hr:163:686414
Pilić, Ivona
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical analysis

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Pilić, I. (2022). Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:686414

Pilić, Ivona. "Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:686414

Pilić, Ivona. "Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:686414

Pilić, I. (2022). 'Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 13 July 2024, https://urn.nsk.hr/urn:nbn:hr:163:686414

Pilić I. Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2022 [cited 2024 July 13] Available at: https://urn.nsk.hr/urn:nbn:hr:163:686414

I. Pilić, "Ukupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:163:686414

Metadata
TitleUkupni polifenoli i antioksidativna aktivnost dodataka prehrani za liječenje upalnih bolesti crijeva
Title (english)Total polyphenols and antioxidant activity of dietary supplements for the treatment of inflammatory bowel diseases
AuthorIvona Pilić
MentorDaniela Amidžić Klarić (mentor)
Committee memberDaniela Amidžić Klarić (predsjednik povjerenstva)
Committee memberAna Mornar Turk (član povjerenstva)
Committee memberLaura Nižić Nodilo (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical analysis)
Zagreb
Defense date and country2022-09-02, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Upalne bolesti crijeva, Chronova bolest i ulcerozni kolitis, su kronične relapsirajuće bolesti koje pogađaju milijune ljudi diljem svijeta te narušavaju njihov svakodnevni život. Budući da polifenoli, sekundarni metaboliti biljaka, imaju antioksidativni i protuupalni učinak, cilj ovog rada bio je procijeniti kvalitetu dodataka prehrani za liječenje upalnih bolesti crijeva obzirom na sadržaj polifenola te odrediti antioksidativnu aktivnost istih. Sadržaj ukupnih polifenola u analiziranim uzorcima određen je spektrofotometrijskom metodom korištenjem Folin-Ciocalteu reagensa, dok je antioksidativna aktivnost procijenjena DPPH testom. Sadržaj polifenola značajno je bio veći u jednom multipreparatu tri biljne vrste: kurkuma, indijski tamjnanovac i crni papar. Nadalje, sadržaj ovih biološki aktivnih tvari u monopreparatima kurkume bio veći nego kod ostalih analiziranih monopreparata. Dobiveni rezultati upućuju na iznimnu kvalitetu dodataka prehrani za liječenje upalnih bolesti crijeva te se analizirani uzorci mogu smatrati dobrim izvorom polifenolnih sastavnica, dok je antioksidativna aktivnost ispitivanih dodataka prehrani u skladu sa sadržajem ovih biološki aktivnih sastavnica.
Abstract (english)
Inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are chronic relapsing diseases affecting millions worldwide and disrupting their daily lives. Since polyphenols, the secondary metabolites of plants, have an antioxidant and anti-inflammatory effect, the aim of this work was to evaluate the quality of dietary supplements for the treatment of inflammatory bowel diseases with regard to the content of polyphenols and to determine their antioxidant activity. The content of total polyphenols in the analyzed samples was determined by the spectrophotometric method using the Folin-Ciocalteu reagent, while the antioxidant activity was assessed by the DPPH test. The content of polyphenols was significantly higher in a multi-botanical preparation of three plant species: turmeric, Indian frankincense and black pepper. Furthermore, the content of these biologically active substances in turmeric monopreparations was higher than in other analyzed monopreparations. The obtained results point to the exceptional quality of dietary supplements for the treatment of inflammatory bowel diseases, and the studied samples can be considered a good source of polyphenolic components, while the antioxidant activity of the tested dietary supplements is in accordance with the content of these biologically active components.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:686414
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2024-09-02
Terms of useLicence In copyright icon
Created on2022-09-05 15:09:22