Objectives: Increased use of herbal drugs and dietary supplements among pregnant women, because of their feeling of harmlessness and safety, may lead to unreasonable use of such products and enhance the risk of unfavorable pregnancy outcome. To ensure efficient and safe use of products for self-medication during pregnancy, the role of public pharmacists as the most accessible healthcare professionals is outstandingly important. The goal of this research is to examine knowledge, attitude and experience of pharmacists in the Republic of Croatia with regard to usage of herbal drugs and dietary supplements during pregnancy. Respondents and Methods: In this work research has been carried out on a sample of 98 public pharmacists. The participants in the research were masters of pharmacy with at least one year of internship in public pharmacy. The research was carried out by means of an anonymous questionnaire created for this purpose. At the beginning of the survey questionnaire sociodemographic data of respondents (age, sex, years of working experience in pharmacy, size of city where pharmacy is located, further education) were collected. Remaining questions were about their knowledge, experience and attitude in application of herbal drugs and dietary supplements during pregnancy. Research was carried out in public pharmacies on the territory of Croatia in the period from May to July 2020. Results: Majority of pharmacists (60 %) advise pregnant women several times a month. Pregnant women mostly seek counsel related to digestive problems linked to pregnancy and related to symptoms of cold/viruses. The majority of respondents (60-79 %) advise the use of herbal drugs and dietary supplements in a case of nausea, vomiting, diarrhea, constipation or hemorrhoids. Most commonly used products contraindicated during pregnancy were those containing bearberry (N = 20) and herbal drugs with anthracene derivatives (N = 7). Observed side effects were mostly digestive problems (N = 11) linked to use of products containing iron (in isolation or within multivitamin formulae), omega 3 fatty acids or ginger. In three pregnancies pharmacists reported clinically relevant interaction between iron and levothyroxine. Slightly more than half of respondents have stated their dissatisfaction related to the availability of official information on usage of herbal drugs and dietary supplements during pregnancy. To advise pregnant women, the majority of pharmacists use easily obtainable sources of information, written instruction and declaration on dietary supplements and/or professional literature. Almost all pharmacists believe that herbal drugs and dietary supplements should be handed out after professional counsel. Half of them are concerned about the safety of use of dietary supplements during pregnancy. Despite the fact that the vast majority of respondents consider themselves competent in advising pregnant women about the application of herbal drugs and dietary supplements, 98 % still expressed the need for further professional education in this domain. Conclusions: Public pharmacists, thanks to their knowledge and skill as well as their accessibility to the patients, have the opportunity to counsel pregnant women on rational use of herbal drugs and/or dietary supplements related to diseases appropriate for self- medication. They are able to recognize if some product is contraindicated, causes side effects or enters into interactions. Taking into account the uncertainty in therapy decision making, stated by pharmacists, with regard to self-medication of pregnant women, pharmacists are in need of further education to improve their professional competence linked to this topic. Only then will they be able to offer adequate pharmaceutical care to pregnant women.