Objectives There is a large number of different topical preparations on the market with different forms and doses of vitamin C that are used to slow down the aging process of facial skin. The aim of the specialist work is to review scientific studies in which the topical effect of vitamin C on the aging process of facial skin was examined in order to systematize the results of research. Material/Patients and Methods For the purpose of writing this specialist paper, the electronic database PubMed was searched. The search included scientific studies that examined the topical effects of vitamin C on the aging process of the skin. The studies that have examined different combinations of vitamin C with a number of synthetic as well as natural active ingredients were also included. The selection of scientific studies was limited to clinical studies published in English. All of those studies that had full texts available or exceptionally only abstracts were reviewed. Results A total of 23 studies examining the effectiveness of topical vitamin C on the skin aging process were examined. These studies have proven the effective effect of vitamin C in collagen biosynthesis, increasing the density of skin papillae, as an antioxidant and increasing elasticity. Several studies have shown a good tolerability of treatment. Innovative vitamin C formulations with different delivery systems have proven to be good at solving stability problems. Combinations of vitamin C with other substances have contributed to achieving better efficacy. Conclusion Topical preparations with vitamin C have shown significant effects in the aging process of the skin. The addition of other active substances as well as innovative pharmaceutical forms can ensure the stability of vitamin C while maintaining efficacy. Nevertheless, additional studies are needed in addition to long-term monitoring of patients after discontinuation of therapy, which will contribute to better insight into the efficacy and safety of topical vitamin C administration.